Biomedical subjects
F Rivera Hueto
Publications and source records attributed to F Rivera Hueto.
Cutaneous sarcoid granulomas with oat cell carcinoma of the lung.
A case of a 68-year-old male is presented, with a history of asymptomatic slight scaling, infiltrated patches with an atrophic central portion, of 3 months of evolution on the face and trunk. A chest X-ray showed an oat cell lung carcinoma, with the same evolution time as the cutaneous lesions. Several cutaneous biopsies showed typical sarcoid granulomas, with profuse giant cells. An immunohistochemical study showed B-cell-positive granulomas. The patient was treated with cytostatic drugs and prednisone, leading to cutaneous, radiological and clinical complete regression of the lesions. We think that this case corresponds to a tumor-related cutaneous sarcoid granuloma reaction.
[Postoperative gastritis due to alkaline reflux. Our results].
We present the results of a retrospective study carried out on 23 patients with alkaline gastric reflux (AGR) verified through endoscopy, biopsies and Tc99m HIDA, which were operated on in our department with Y of Roux, Braun, Henley as the correction techniques of this pathology. The criteria of surgical indications were evaluated in these patients as also the results obtained in reference to residual symptoms and changes in the histologic and gammagraphic patterns.
[Non-specific chronic gastritis and gastric dysplasia, what is their clinical values?].
Although nonspecific chronic gastritis and gastric dysplasia are considered as risk factors in the development of gastric cancer, the magnitude of this risk has not been well established. We made an endoscopic and histologic follow-up of 24 patients with an initial diagnosis of atrophic chronic gastritis and some degree of dysplasia over a period of 8 years. The first study revealed slight dysplasia in 8 patients, moderate dysplasia in 13 and severe dysplasia in 3. In our observation, dysplasia considered overall shows a probability of almost 54% of evolution to regression. In our study, the association of atrophic chronic gastritis and severe dysplasia is a reliable marker of gastric cancer. We think it is opportune to carry out periodic follow-ups by endoscopy and biopsy of patients with chronic gastritis and dysplasia.
[Intestinal melanomas. Current status].
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[Intestinal bypass. Reconversion possibilities according to the microstructure and enzymatic activity of the jejunum and ileum].
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[The assessment of colonic polyps found via colonoscopy].
AIM: To evaluate the histopathological characteristics of colonic polyps, found during colonoscopy examination and endoscopic polypectomy, and their relation to age, tumor location, sex, histological type and degree of epithelial dysplasia. MATERIAL AND METHODS: Between 1996 and 1997, 2,465 total colonoscopies were performed at the Gastroenterology Department of the Virgin Macarena University Hospital in Seville. Different size polyps were found in 318 patients who had been referred because of several symptoms/by several centers. The mean age was 59.2 years in men and 61.5 years in women. RESULTS: 446 polyps were removed by endoscopic polypectomy, 32 (7.2%) were hyperplastic polyps, 402 were adenomas (90.2%) and 12 (2.6%) were adenomas with adenocarcinoma. Seventy-five percent of adenomas were located in the left colon and rectum and 25% in right colon. Hyperplastic polyps were found in left colon. Of the polyps removed, 55.1% were smaller than 1 cm, 26.5% were between 1 and 2 cm and 18.4% were between 2 and 7 cm. Histopathologic study of adenomas revealed that 17% were villous adenoma, 80% were tubular adenomas and 3% were tubulovillous adenomas. Adenocarcinomas were found in 12 (2.8%) adenomas. Of the adenomatous polyps, 87.4% had low-grade dysplasia and 12.6% high-grade dysplasia. Statistical analysis showed a strong correlation between size of adenoma and degree of dysplasia (p < 0.05). Similar significant relation was found between histological type and size (p < 0.05) but there were no statistically significant differences between location, sex or age, and degree of dysplasia (p < 0.05). CONCLUSIONS: Size of colonic polyps is related to epithelial dysplasia and histological type (p < 0.05). No correlation was found between location, sex or age and degree of dysplasia.