Biomedical subjects

F Robustelli

Publications and source records attributed to F Robustelli.

14 recordsLinked to original sources

PubMed1985

[Hypertrophic gingivitis caused by verapamil].

We observed gingival hyperplasia, similar clinically to the hyperplasia caused by diphenylhydantoin during the last 11 months in two patients treated by verapamil, suffering from angina pectoris pains. In Case I discontinuation of the calcium antagonist resulted in marked regression of the gingival hyperplasia. Evidence points to a strong relationship between the gingival hyperplasia and the administration of verapamil. Further studies are required to confirm definitively the relationship between the administration of verapamil and gingival hyperplasia, its incidence, and the correlation with local factors.

Angina Pectoris↗

PubMed1973

[Conditioning of active type avoidance in the rat : effect of the interval between conditioned stimulus and unconditioned stimulus].

Lengthening the time interval between the conditioned stimulus and the unconditioned stimulus increases the number of active avoidance conditioned responses in subjects that have been trained to a stable level of performance in many previous conditioning sessions. In the present research, rats chosen from a population specially selected for low rates of avoidance conditioning have been used. In addition to this characteristic, subjects were chosen for the exhibition of an apparent absence of retention from one day to another. The dependency of the number of conditioned responses on the time interval between conditioned stimulus and unconditioned stimulus may lead to wrong evaluation of the subjects' conditioning level. In fact, the level of conditioning may be attributed to either learning or memory processes when in many cases it is determined only by the latency time of the conditioned response. The conditioned response has no possibility of manifesting itself when its latency time exceeds in length the time interval between conditioned stimulus and unconditioned stimulus.

Animals↗

PubMed1973

[Methods for grading the strength of passive conditioned avoidance reaction].

Three methods for obtaining passive avoidance conditioned responses of different strength are described. The first method consists of delayed reinforcement, constituted by a foot-shock, in the conditioning trial. The second method corresponds to the "detention" procedure, through which the animal is kept in one part of the apparatus for some time, after the conditioning trial. The third method consists of using foot-shocks of different strength in the conditioning trial. This method, however, is not advisable in most cases, since it produces strong differences in the subjects' level of arousal after conditioning and therefore a different reactivity to the various treatments.

Animals↗

PubMed1972