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Biomedical subjects

F Rocca

Publications and source records attributed to F Rocca.

At least 55 records · Page 3Linked to original sources
PubMed1984

A prospective study of relationships between benign gastric ulcer, Candida, and medical treatment.

Results of a multicenter prospective study on the relationships between benign gastric ulcer, Candida, and medical treatment is reported. In a group of 66 patients, mycetes were seen in six cases (9.1%). Candida-contaminated ulcers were diagnosed solely by histological examination, with periodic acid-Schiff staining being more effective than hematoxylin and eosin staining. All contaminated ulcers were healed by treatment either with cimetidine alone, or combined cimetidine-carbenoxolone, without antimycotics. No cases of Candida-contaminated ulcers were seen after 6 wk of treatment. The finding of contamination was more common in older patients. Under the conditions of our study, Candida-contamination of benign gastric ulcers does not affect the rate of healing, does not need specific treatment, and has no particular endoscopic features. Cimetidine or carbenoxolone treatment was not associated with persistence of the fungus.

Age Factors↗
PubMed1981

Radiolucent gallstone dissolution with bedtime UDCA administration.

26 patients (20 females and 6 males, mean age 40.5 years +/- SEM 2.20, mean weight 60.2 kg +/- 1.98) with radiolucent gallstones of diameter less than or equal to 10 mm were treated for 6 months with ursodeoxycholic acid (UDCA), a single dose of 600 mg at bedtime. The rate of partial + complete dissolutions was 85%, reaching 100% for gallstones of less than 4 mm diameter. No side effects were observed. In a similar series of patients treated with UDCA t.i.d. at mealtimes (10--12 mg/kg/day) a slightly lower dissolution rate was obtained but the difference was not statistically significant.

Adult↗
PubMed1976

Effect of analgesic agents on emptying of the gallbladder in man.

A controlled study of the clinical pharmacology of the biliary tract has been made. The rate of gallbladder emptying induced by a fatty meal was taken as a parameter for assessment of the inhibitory effect of indoprofen, a new analgesic-anti-inflammatory drug, pentazocine and morphine. The compounds were administered as single doses by iv (indoprofen and pentazocine) or im (morphine) injection. Indoprofen up to 400 mg had no effect, whereas morphine and pentazocine exerted a significant inhibitory effect on emptying of the gallbladder. Adverse reactions of clinical significance were associated with morphine and pentazocine, but were negligible with indoprofen.

Adult↗