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Biomedical subjects

F Ruggieri

Publications and source records attributed to F Ruggieri.

29 records · Page 2Linked to original sources
PubMed1977

Delayed closed endomedullary osteosynthesis in complicated fractures of the femur and tibia.

The results obtained with delayed closed endomedullary osteosynthesis in 230 cases are considered. This method greatly extends the use of endomedullary nailing to open fractures and those in which controindications of a mechanical nature (multiple fractures, or at several levels) rule out the immediate use of implants. The techniques proposed (osteosynthesis with triflanged nail in fractures of the diaphysis and osteosynthesis with double Rush nails in metaphysio-diaphysis fractures) have two advantages. Due to the non opening of the fracture focus there is minimal risk of infection and early restoration of function.

Adult↗
PubMedDate not supplied

Double-blind crossover trial to compare the activity of nedocromil sodium and placebo in antigen challenge.

In a double-blind crossover placebo controlled study, the inhibitory effects of three different doses of nedocromil sodium on the immediate bronchoconstrictor response to antigen challenge were compared with a placebo. All the test treatments were inhaled three hours before challenge. Four asthmatic patients took part in the study and the test treatments were taken in a randomized order. All three doses of nedocromil sodium significantly reduced the bronchoconstrictor response and protected the patients against antigen challenge, compared with placebo. The highest dose of 2 mg was the most effective dose. All test doses of nedocromil sodium were safe and well tolerated by the patients.

Administration, Inhalation↗
PubMedDate not supplied

Prevention of non-specific bronchial hyperreactivity. Dose-dependent effect of sodium cromoglycate metered dose aerosol.

The protective effect of different doses of sodium cromoglycate (4 mg, 12 mg and 20 mg) given as pressurized aerosol on fog-induced bronchoconstriction were investigated in three different groups of asthmatic patients. Premedication with the active drug was compared versus absence of premedication. The authors discuss their results by a statistical analysis of the FEV1 variations. Sodium cromoglycate effectively prevents fog-induced bronchoconstriction with a clear dose-dependent effect.

Adolescent↗