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Biomedical subjects

F S Mishkin

Publications and source records attributed to F S Mishkin.

At least 55 records · Page 3Linked to original sources
PubMed1977

67Ga lung scan. An aid in the differential diagnosis of pulmonary embolism and pneumonitis.

Twenty-three patients patients with clinical signs of pulmonary embolic disease and lung infiltrates were studied to determine the value of gallium citrate Ga 67 lung scan in differentiating embolic from inflammatory lung disease. In 11 patients without angiographically proved embolism, only seven had corresponding ventilation-perfusion defects compatible with inflammatory disease. In seven of these 11 patients, the gallium 67 concentration indicated inflammatory disease. In the 12 patients with angiographically proved embolic disease, six had corresponding ventilation-perfusion defects compatible with inflammatory disease. None had an accumulation of 67Ga in the area of pulmonary infiltrate. Thus, ventilation-perfusion lung scans are of limited value when lung infiltrates are present. In contrast, the accumulation of 67Ga in the lung indicates an inflammatory process. Gallium imaging can help select those patients with lung infiltrates who need angiography.

Acute Disease↗
PubMed1977

Division of spermatic vessels in orchiopexy: radionuclide evidence of preservation of testicular circulation.

Satisfactory intrascrotal position of the testicles was achieved by dividing the spermatic vessels, leaving the vas deferens intact, in 3 patients with undescended testes. A postoperative scrotal scan provided objective means of evaluating the adequacy of testicular circulation. To determine the efficacy of various procedures for orchiopexy for undescended testes we suggest that postoperative evaluation include radionuclide imaging of the scrotum.

Adolescent↗
PubMed1977

Differential diagnostic features of the radionuclide scrotal image.

Differential diagnosis of scrotal lesions is aided by correlating radionuclide images with clinical findings. Subacute torsion is associated with peripheral hyperemia and can be mistaken for an inflammatory process; however, in a review of 128 studies, torsion and orchiectomy were the only processes encountered which had a center truly devoid of activity on the tissue phase compared to the normal side. Other lesions such as acute inflammation, abscess, hematoma, and hemorrhagic tumor may superficially appear to lack central activity but invariably contain at least as much activity when compared to the normal side.

Adolescent↗
PubMed1976

Direct recording on rectilinear scan images on 4x5-in. film.

Rectilinear scans are usually recorded on 14 X 17-in. x-ray film. This is costly both in terms of film and storage space. Using 4 X 5-in. film instead of the larger film will reduce this cost. An Ohio-Nuclear Model 84FD dual-probe 5-in. scanner was converted for the production of scan images directly on 4 X 5-in film (Kodak SO-79 nuclear medicine film). The smaller images may be viewed directly on a standard x-ray viewbox, or they may be projected if a larger image is desired. The image quality is excellent. This system has replaced the 14 X 17-in. film at our institution.

Photography↗
PubMed1975

Radionuclide imaging in intrascrotal lesions.

Twenty-three patients with a variety of intrascrotal lesions were studied by means of imaging after the intravenous injection of sodium pertechnetate Tc 99m. The features of the radionuclide image correlated well with the clinical course or findings at surgical exploration or both. The conditions in which this technique was helpful in diagnosis included testicular torsion, acute inflammatory lesions, abscess, and hematoma.

Abscess↗
PubMed1975

Noninvasive study of extremity perfusion by potassium 43 scanning.

In nine patients with lower extremity symptoms of arterial insufficiency, potassium chloride K 43 was injected intravenously during rest, reactive hyperemia, or exercise. Decreased radioactivity in muscle tissue was observed to correspond with symptoms, physical findings, Doppler ultrasound pressures, and angiographic findings in all six who had the procedure. Studies following surgical endarteractomies in two, a bypass procedure in one, and exploration without attempted reconstruction in one showed good correlation with postoperative symptoms, physical findings, and pressure measurements using Doppler ultrasound in three of four patients. The fourth patient showed no change on the postoperative study despite clinical imporvement. These findings suggest that intravenously administered radioactive potassium provides a noninvasive means for demonstrating the perfused muscle mass of the extremities with delieation of ischemic areas. The risk of arterial puncture is eliminated, and the ability to visualize perfusion patterns during exercise is unique to this method.

Adult↗
PubMed1975

Abnormal radionuclide cerebral angiograms and scans due to seizures.

The effect of recent seizures on the brain scan was determined in a retrospective study of patients who had had seizures. All patients who underwent brain scanning within eight days of seizures and who did not have a specific intracranial lesion were included. The 99mTc-pertechnetate cerebral angiogram and/or delayed scan was abnormal in 73% of 22 patients. The data suggest that if seizures occur within six days of the brain imaging, the image is likely to be abnormal.

Adolescent↗
PubMed1975

Vascular displacement diagnosed by cerebral radionuclide angiography.

Findings were reviewed in twelve patients who had contrast and radionuclide cerebral angiograms interpreted as showing displacement of the anterior or middle cerebral arteries on either study. The radionuclide angiogram detected 3 of 8 displacements of the anterior cerebral artery and 9 of 10 displacements of the middle cerebral artery. In two cases the radionuclide study suggested displacement of the middle cerebral artery when in fact it was occluded in one and normal in the other. Radionuclide angiographic detection of major cerebral artery displacement provides valuable interpretative data, particularly when the middle cerebral artery is involved.

Adult↗