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Biomedical subjects

F S Tkach

Publications and source records attributed to F S Tkach.

At least 19 recordsLinked to original sources
PubMed1987

[Surgical treatment of diffuse toxic goiter associated with autoimmune thyroiditis].

An experience of the clinic with the surgical treatment of diffuse toxic goiter associated with autoimmune thyroiditis for the recent 16 years has been generalized based upon 258 observations. Long-term results followed in 73.6% of the patients show that an improved method of operation thought to be less radical gives good results. An immune depressive effect of the operation was noted. The investigation facilitates positive solution of the problem of the expediency of the surgical treatment of the complicated form of toxic goiter having indications for surgery.

Adolescent↗
PubMed1978

[Surgery of thyrotoxicosis associated with diseases of the central nervous system].

Studies on 1432 thyrotoxicosis cases attracted the attention to a relatively high incidence (7.7%) of its association with damage to the central nervous system. 27 of 110 patients with combined type of thyrotoxicosis developed malignant exophthalmos. On the grounds of the studies of long-term results of the surgical treatment of these cases one could come to the conclusion, that surgical treatment of combined types of thyrotoxicosis was an efficient method. The clinic recommends complex preoperative management and a postoperative care procedure.

Adolescent↗
PubMedDate not supplied

[Diffuse toxic goiter associated with autoimmune thyroiditis].

A study of 190 patients with diffuse toxic goiter combined with autoimmune thyroiditis has revealed some clinical features: a torpid course and a solid-elastic consistency of the thyroid. In 37.4% of the cases autoimmune thyroiditis was combined with a severe form of thyrotoxicosis. The combined form of diffuse toxic goiter correlated with a greater frequency of the detection of thyroid autoantibodies to thyroglobulin and microsomal antigen (in 83 and 78.3% of the patients respectively) as compared to the common form of diffuse toxic goiter (in 47.3 and 48.1%). A study of the hormonal thyroid status of 43 patients with diffuse toxic goiter combined with autoimmune thyroiditis showed that T3, T4 and TTH levels in patients with the presence of autoantibodies to thyroid antigens did not differ from the levels of these hormones in the common form of diffuse toxic goiter, and in the group of the patients with the absence of autoantibodies there was a tendency to the development of T3-toxicosis. The absence of pathognomic symptoms in combined forms of diffuse toxic goiter makes their preoperative diagnosis difficult. Interrelationship of the hormonal thyroid status and humoral antithyroid immunity was noted.

Adolescent↗