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F Sánchez-Valverde

Publications and source records attributed to F Sánchez-Valverde.

7 recordsLinked to original sources
PubMed2002

[Breast-feeding in Navarra].

The state of breast-feeding in our autonomous community between 1986 and 1993 is reviewed. Two comparable Navarrese neonatal groups from our main maternity hospital are studied. The prevalence of the different types of breast-feeding at the time of discharge from the maternity hospital is compared, as well as monthly rates until the sixth month of life. The following conclusions can be drawn from this study: 1. The category of breast-feeding in Navarra is type 1 of the WHO. 2. Breast-feeding is abandoned in an early and massive way throughout the first six months of life in Navarra, with figures for this practice being undetectable by the sixth month. 3. There are barely any significant differences between the figures for 1986 and 1993.

English Abstract↗
PubMed2001

Heat-shock protein 70-1 and HLA class II gene polymorphisms associated with celiac disease susceptibility in Navarra (Spain).

Heat shock proteins (HSP) are thought to play a role in the immune response making probable their contribution to celiac disease (CD). We studied the polymorphisms in the 5' regulatory region of the HSP70-1 gene and performed genomic HLA-DQ and -DR typing in 128 CD patients and 94 healthy controls from Navarra (Spain). The frequency of the C allele of the HSP70-1, characterized by the intermediate electrophoretic mobility of DNA, was significantly increased among CD patients (64.5% vs 37.2%. p <1 x 10(-7)). When subjects were stratified by the HLA II genotype, differences were statistically significant between DR3-negative or DR3-DQB1*02-negative CD patients and matched controls. Homozygosity for the DQB1*02 allele was present in 48.4% of CD patients and 12.8% of controls (OR = 6.4; CI:3.1 to 13.8; p <1 x 10(-7)). Similar increased risk was observed for DQB1*02/*02, DRB1*03/-, or DRB1*03/07 patients. Furthermore, those individuals expressing the classical HLA alleles in CD (DQB1*02/*02, DRB1*03/*07) who also carried the HSP70-1 CC genotype were twelve times more likely to develop the disease than the matched controls. We therefore conclude that although HSP70-1 gene does not seem to be primarily associated with CD, it might be a component of the high risk haplotype, playing a role as an additional predisposing gene for the disease.

5' Untranslated Regions↗
PubMed1998

[Infant mortality and sudden infant death in Navarra between 1985 and 1996].

OBJECTIVE: The objective of this study was to obtain an accurate register of the deaths of children less than one year of age in order to discover the real infant mortality (IM) rate in Navara and its trend during the period between 1985 and 1996, a well as to investigate the deaths by sudden infant death (SID) in the same period and their relationship to the prone position during sleep. PATIENTS AND METHODS: Infant mortality was determined by detailed examination of all certified deaths. Research into possible nonregistered deaths was also carried-out. The sources of information included the archives and registers of the pediatric and obstetric wards and pathology departments of all hospitals. Deaths codified as 798.0 (CIE9 infinity R) were included in the study as death by SID. To determine sleeping posture. In the second semester of 1996, a survey was carried out on a sample of 285 children of under 6 months of age. The survey's model is the same as that published previously. RESULTS: In the period of 1985 to 1992, IM was 12.33 per thousand live births. The SID rate was 1.30/1,000 live births. The prevalence of the prone position is unknown. In the period between 1993 and 1996, IM decreased to 5.84/1,000 live births and this decrease was proportional in both the neonatal and postneonatal components. The rate of SIM decreased to 0.44/1,000 live births. At the beginning of 1993, 86% of the children slept in the prone position, in 1994, 38% and in 1996, only 23%. CONCLUSIONS: Trustworthy data in Navarra shows a decrease in IM of more than 50% from 1993 on. The SID rate also decreased by 65%, coinciding with a massive drop in the use of the prone position during sleep.

Humans↗
PubMed1993

Trans fatty acid content of human milk in Spain.

The C18 fatty acid fraction of 38 samples of mature human milk from Spanish women was analyzed using capillary gas chromatography. The average content of trans fatty acids found in these samples represented 0.95% of total fatty acids. This value is lower than the percentage found in human milk from other developed countries in which the consumption of hydrogenated fat is higher. Trans fatty acid content in human milk has been related to the types of fats and oils present in the diets of the nursing mothers. According to the results obtained in this survey, we can also conclude that the amount of trans forms in breast milk lipids is lower than the trans content found in infant formulas in Spain.

Adolescent↗
PubMed1984

[Idiopathic varicocele in children].

The authors present their experience with ten children operated on for left-sided idiopathic varicocele over a period of seven years. The treatment was high ligature of the spermatic vein with a favorable outcome in all cases. The histology of the testes, seen in biopsy, demonstrated a variable degree of damage. For this reason the authors recommend that this operation should be done in childhood in order to avoid problems of subfertility or infertility in adult life.

Adolescent↗
PubMedDate not supplied

[Measurement of stool composition in children with celiac disease using near-infrared reflectance spectroscopy].

Celiac disease is a disorder caused by gluten-sensitivity which, when manifested in its classical digestive form, frequently presents a malabsorption syndrome. The aim of this study is to evaluate the faecal composition in celiac children with malabsorption syndrome at the moment of diagnosis by using near-infrared reflectance spectroscopy and to compare it with that of healthy children. Thirty children with biopsy-proven celiac disease and 86 age-matched control children were recruited in our study. Children collected 24 hour faecal specimens and the analyses of faeces, water, fat, nitrogen and sugar were performed using near-infrared reflectance spectroscopy. Results show that celiac children daily eliminate a significantly greater quantity of water, fat, nitrogen and sugar than those in the control group. This might be due to the higher weight of faeces eliminated in the celiac group and, of course, to their celiac condition. Of all the nutrients, faecal fat is the substance which undergoes the greatest change, indicating that this nutrient continues to be the best parameter for dealing with patients with malabsorption syndrome. Near-infrared reflectance spectroscopy appears to be a useful tool for assessing stool composition in celiac disease.

English Abstract↗