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F Salazar

Publications and source records attributed to F Salazar.

8 recordsLinked to original sources
PubMed1989

[Combined chemotherapy with the FEM protocol in advanced gastric cancer].

Thirty one patients with diagnosis of Gastric Cancer were admitted in this study. Median age was 71 years (range 24-82). Twenty two were male. No one had previous chemotherapy. Functional capacity was 0-1 in 26/31 (60.6%). More common symptoms were: loss of weight 21/31 (75.1%) and abdominal pain in 13/31 (40.3%). Ten patients were Borrmann III and nine Borrmann IV. Twenty one had surgery: 12 palliative gastrectomy and 9 exploratory laparatomy. Twenty three cases were adenocarcinoma and 8 undifferentiated carcinoma. FEM regimen was administered (5 Fluoruracil 600 mg/m2/day 1 and 8, Epidoxorubicin 30 mg/m2/day 1 and Mitomycin 10 mg/m2/day 1). Ten of 24 patients (41.7%) achieved partial remission with a median survival of 10.5 months. Three patients achieved subjective response with a median survival of 6 months. Median survival for the non response was 3 months (range 2-7 months). Survival difference between responders and no responders was statistically significant. Survival among the adjuvent group was 5.7 months (range 2-16 months). One out of three patients survived without evidence of disease at the end of this study. Twenty three patients died and 5 were lost to follow up. Alopecia was the most common secondary effect in 74%, nausea and vomiting in 60% and leukopenia below 3000 x mm3 in 54%. Cardiotoxicity was not documented in any case.

Adult↗
PubMedDate not supplied

[Stevens-Johnson syndrome associated with esophageal stenosis].

Stevens-Johnson syndrome consists of inflammatory bullous lesions of the skin and mucous membranes and seems to be associated to several pharmacologic and/or infectious triggering factors which might share a common immunologic way. Esophageal stenosis secondary to Stevens-Johnson syndrome is very rare. During the last 40 years, only two cases in children have been reported. In the present work, we report clinical features and anesthetic management of a 6-year-old girl requiring seven general anesthesia procedures with ketamine and isoflurane for correction of esophageal stenosis.

Anesthesia↗