[Meteorological changes and myocardial infarct. Case contributions].
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Biomedical subjects
Publications and source records attributed to F Salvati.
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A case of transient bisalbuminemia secondary to pancreatitis with ascites is described. The bisalbumin was of the "fast" type and disappeared after sixty days of therapy. The clinical and pathological implications of these findings are discussed.
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Pelger-Huet's granulocyte abnormality is discussed. This abnormality is characterized by the presence of granuloyctes with a non-segmented nucleus and thick nuclear chromatin gathered in large lumps, in contrast with the "youthful" appearance of the nuclei. In humans, a real Pelger-Huet abnormality with familial character and dominant autosomic transmission is distinguished together with a pseudo-Pelger in which the granulocytes assume cytological features similar to those typical of the constitutional abnormality but whose genesis is closely correlated to the disease of which these are an epiphenomenon.
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Anaemia is common in renal insufficiency and has various causes: 1) depressed marrow production of red cells, probably due to reduced production of erythropoietin, though the possibility of direct marrow inhibition on the part of uraemic toxins cannot be ruled out, together with iron deficiency, as occurs in prolonged dialysis management; 2) greater red cell destruction attributable to extraglobular factors and other mechanisms (microangiopathy, drugs, etc.); 3) greater blood loss following thrombocytopenia, reduced platelet adhesivity and agglutinability, dialysis. The main premisses on which the treatment of anaemia of uraemic patients is based are discussed.
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