Biomedical subjects
Publications and source records attributed to F Sell-Salazar.
The author presents a review and actualization of West syndrome related knowledges, ethiological issues, clinics, and the EEG tracings. It is also include a literature review about different therapeutic treatments emphasizing the use of vigabatrin.
OBJECTIVE: To make a specific review of the definition and symptomatology of Gilles de la Tourette syndrome. DEVELOPMENT AND CONCLUSION: We made an basic syndrome evaluation and at the same time established a relationship with/between the most significant co-morbid features. We also refer briefly to current drug treatment and dosage and mention some of the most relevant side-effects of these drugs. The exact etiology of this disorder is still not fully understood but it is thought to be due to autosomal dominant inheritance, with marked penetration in males.
Juvenile dermatomyositis is part of the idiopathic inflammatory myositis group of diseases, presenting acute or chronic multisystemic inflammatory injury, that mainly affects muscles and skin. It s incidence is 4/1,000,000, prevailing in women and Caucasians, with symptoms starting between 5 14 years of age. The etiology is unknown, nevertheless is well recognized the role of vasculitis produced by autoantibodies, such is responsible for the damage on skin and muscular microvasculature. The acute or chronic complications and the neuropathic manifestations (cerebral vasculitis and peripheric neuropathy) are rare, and both are the result of the same autoimmune vasculitis injury.
INTRODUCTION: Attention deficit/hyperactivity disorder (ADHD) is an early onset childhood condition that is estimated to occur in 7-10 % of school age children. DEVELOPMENT: There are two specific syndromes: a) Attention deficit disorder, without hyperactivity; b) A more complex syndrome, with hyperactivity, with traits of impulsivity, accompanied by attention deficit disorder. The etiology of this syndrome is still unclear, but there have been some hypothesis about hypoperfused areas in the frontal lobe, in some patients where PET has been available. There have been also some response to stimulants; which leads to the conclusion that there is some relation with neurotransmitters like noradrenaline and dopamine, as a determinant factor in the origin of this process. Among 80% of children with this diagnosis, respond positively to the use of psychostimulants. Although, there are some cases that respond poorly, which are evaluated in this review. CONCLUSION: This article also highlights the importance of multidisciplinary assessment, in the diagnosis and treatment of these cases. It gives a clinical characterization of the syndrome, following DSM IV guidelines. Finally, it addresses, the use of non stimulant drugs, that can be helpful in the treatment of this disorder.
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