[Postoperative infection in hip and knee surgery: does a relationship exist between hypercoagulability and immunomodulation induced by the transfusion practice?].
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Biomedical subjects
Publications and source records attributed to F Seral Iñigo.
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Among 79 patients candidates to hip (53) and knee (26) replacement an evaluation was made of the influence of a two-week program with LMWH on the evolution of hypercoagulability markers: D-D, TAT, and F1 + 2. Measurements were performed by ELISA preoperatively and on days 1, 7 and about 45 postoperatively; in the latter, two extraction intervals were considered: < or = 45 days and > 45 days. With both surgical modalities, D-D and F1 + 2 peaked at 7th day postoperatively, whereas TAT peaked on day 1. Among D-D and F1 + 2 values quantitated on day 7th and the extraction interval < or = 45 days, no significant differences were obtained (Z < 2.64). The hypercoagulative chronicity exhibited by D-D and F1 + 2 during the first month and a half after this surgery, might require in some cases a more prolonged thromboprophylaxis.
We have carried out a biomechanical study of the forces acting on the Grosse-Kempf intramedullary nail to determine those which most affect its structure. We have used finite element analysis to assess the distribution of compression, flexion and torsion forces. The qualitative and quantitative distribution of the tension on the surface of the nail has been observed. We have shown that the torsional force is most important and it is exerted in the posterior part of the nail where there is a change from the unslotted to the slotted section.
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