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Biomedical subjects

F Serban

Publications and source records attributed to F Serban.

At least 19 recordsLinked to original sources
PubMedDate not supplied

[Glutathione and the redox index in different types of cellular oxidative stress. I. Acrylonitrile (ACN) poisoning].

The professional poisoning with acrylonitrile of some subjects induced a significant decrease of reduced glutathione (81.30%), redox ratio reduced glutathione/oxidized glutathione (90.74%) and "Benzi-redox index" (55.84%) but an increase of oxidized glutathione level (112.6%) as compared to normal controls (100%). This proves the occurrence, in time, of the cellular oxidative stress and/or were obtained.

Acrylonitrile↗
PubMedDate not supplied

[Epidemiology of essential arterial hypertension in collectives of schoolchildren. The prevalence of blood pressure changes].

7,917 pupils in schools, between 10-19 years old, of both sexes, were investigated within an epidemiologic screening, performed in the school milieu, for detecting the prevalence of some risk factors (RF) and of the AT modifications with a view to work out the programmes for the essential arterial hypertension (EAHT) primary prevention. 84.4% of all the pupils in the Vth--VIIIth forms and 93.9 pupils in the IXth--XIIth forms were included in the screening. 422 cases of labile arterial hypertension (LAHT) (5.1%) and 457 of benign arterial hypertension (BATH) (54%) were found. In the children with normal arterial hypertension (NAHT) the following were recorded: 46.5% increases only of the diastolic tension: 44.0% of the systolic-diastolic and 7.1% of the systolic tension respectively. Although present, the differences between the LAHT and BAHT prevalence in the gymnasiums (4.3% and 5.4%) and lyceums (5.5% and 6.4%) are not significant and might be functions of: age, sex, psychomotor development, structure of the respective collectivities, the momentary psychoemotional reactions, lability of the blood pressure, specific to the childhood, several screening difficulties etc. The observations made on the prevalence of the growth of the AT values were correlated with the occurrence at some significant levels of the RF, suggesting the measures to be taken for the steady improvement of the primary and secondary prophylaxis of EAHT in schools.

Adolescent↗
PubMedDate not supplied

[Intervention associated with risk factors for essential arterial hypertension. II. Epidemiologic observations of schoolchildren].

Based on an epidemiological screening of 6411 pupils from 7 schools of different types, the frequency and intensity of the association of 8 risk factors for essential hypertension in a series with increased blood pressure values and in a normotensive one was compared. The frequency of the various studied risk factors was significant especially in the pupils with increased blood pressure values. The average number of risk factors in the two series was unsignificant. The intensity of 2, 3 or 4 risk factors different associations was more marked in the pupils with increased blood pressure values than in the controls. Some risk factors proved to be more frequently involved in multifactorial associations. The importance of such studies for the elaboration of prevention programmes in underlined.

Adolescent↗
PubMedDate not supplied

[The dynamics of ethanol metabolism in patients with chronic alcoholism].

The results of the investigations carried out in alcoholics and nonalcoholics regarding certain aspects of ethanol metabolism are presented. The marked interindividual differences in alcohol blood levels and intergroup differences in acetaldehyde levels, through a projection in dynamic process, are commented upon. The programmed ethanolic load induced changes in blood alcohol, within comparable limits, irrespective of subjects' state. At all intervals of postintake determinations, the acetaldehyde concentrations were higher in the alcoholic subjects. No dose-effect relation between the involved elements (ethanol metabolite) was found.

Acetaldehyde↗
PubMedDate not supplied

[Interventions associated with some risk factors for essential arterial hypertension. I. Epidemiologic observations in adults].

The results of an epidemiological screening followed by the investigation of 9 risk factors for essential hypertension in 1218 individuals with increased values of blood pressure are presented. Stress, overweight and dietary preferences for fats and eggs had the incidence especially in, the age groups over 40 years. Both the individuals with borderline hypertension or arterial hypertension and the controls presented 2, 3 or more associated risk factors of variable intensity, the higher values being recorded in the greater than or equal to 40 years age group. When more than 3 risk factors were associated, the increases in systolic and diastolic pressures were significant. The investigation of 7 biochemical constants revealed that 50% of 190 cases with arterial hypertension presented cholesterol levels higher than 220 mg%. Increased total lipids, free fatty acids and triglycerides levels were also recorded. The results plead for multifactorial prevention programmes.

Adult↗