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Biomedical subjects

F Sh Saliev

Publications and source records attributed to F Sh Saliev.

4 recordsLinked to original sources
PubMed1978

[Morphological characteristics of ground glass hepatocytes in chronic hepatitis and liver cirrhosis].

Histochemical and electron microscopic examinations of liver punctates from 57 patients with chronic hepatitis and cirrhosis of the liver were carried out. "Ground Glass" hepatocytes were found to occur with similar frequency both in patients with HB-antigen in the blood serum and in patients with alcoholic involvement of the liver and no antigen in the blood serum. The presence of HB-antigen in the cytoplasm of such hepatocytes can be detected by staining of the sections with orsein, aldehydethionine and aldehydefucsin. The latter stain is more specific. Electron microscopically, the "Ground Glass" hepatocytes are characterized by marked hyperplasia of agranular endoplasmic reticulum in the lumen of which peculiar filaments are found in the presence of HB-antigen.

Biopsy, Needle↗
PubMed1977

[Morphological characteristics of acute alcoholic hepatitis].

Liver biopsies from 60 patients with acute alcoholic hepatitis (AAH) developing against the background of steatosis, chronic hepatitis and cirrhosis were studied histologically, histochemically and electron microscopically. AAH is characterized by necrosis of hepatocytes with deposition of alcoholic hyalin, obesity of the organ, and polymorphonuclear leukocyte infiltration. Hyperplasia of the smooth endoplasmic reticulum, the appearance of megamitochondria, and an increased amount of peroxisomes reflect the participation of MEOS and the catalase system in alcohol metabolism with a progressive decrease in the activity of alcoholdehydrogenase. Acute alcoholic hepatitis is a connecting link between steatosis and cirrhosis of the liver in which the accompanying autoimmune mechanism and microcirculation disorder followed by activation of lipofibroblasts are conducive to the progression of the pathologic process.

Acute Disease↗