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Biomedical subjects

F Soyinka

Publications and source records attributed to F Soyinka.

11 recordsLinked to original sources
PubMed1987

Bifonazole in the treatment of fungal skin infections in the tropics: a clinical and mycological study.

A study was carried out in 40 patients with various superficial fungal diseases, confirmed by culture or microscopic examination, to assess the therapeutic efficacy and local tolerability of 1% bifonazole cream. Patients with more than one clinical diagnosis at the time of entry were treated according to the number of conditions present. The cream was applied once daily to the affected areas and treatment duration varied according to persistence or resolution of the clinical signs and symptoms in the individual patient. The results were evaluated by clinical and mycological examination 3 and 14 days after the end of treatment. A cure rate of 100% was achieved in cases of pityriasis versicolor, tinea corporis and candidiasis, and 90% in patients with tinea pedis. Clinical signs and symptoms disappeared completely in all but a few patients. No side-reactions were observed in any patient, and patch tests carried out in selected patients with known allergy and those with normal skin showed no evidence of any allergic or photosensitivity reaction to bifonazole.

Administration, Topical↗
PubMed1979

Sexual behavior among university students in Nigera.

Sexual behavior patterns among Nigerian university students and factors influencing them were studied. While permarital cohabitation is common, a large percentage (48%) had their first coital experience between the ages of 22 and 27. Religion does not appear to have a strong inhibiting influence on premarital sex, although it does affect the frequency of changing partners. Contraceptives, although known to almost all the respondents, are not widely used. The use of contraceptives had little influence on premarital cohabitation. Oral-genital, male-male, and female-female sexual practices are very uncommon.

Adolescent↗
PubMed1978

Epidemiologic study of dermatophyte infections in Nigeria (clinical survey and laboratory investigations).

The commonest dermatophyte infection among the referred dermatology cases in Nigeria is tinea pedis, whereas among the surveyed population of school children, the commonest fungal infection was tinea capitis. It was found that the most ubiquitous causative organism for tinea pedis was E. fluccosum, that for tinea capitis was M. audouinii, while that for tinea corporis was T. soudanese. The source of infection of tinea capitis among the school children was found to be most likely the local barber who serviced the schools in all the villages, and this might explain the high incidence rate of T. soudanese in tinea capitis. Tinea pedis infection is believed to be highly favoured by the wearing of shoes among the senior students. Animals were not a major source of transmission of dermatophytes in Nigeria. No new species of dermatophytes has been identified among the cultured organisms.

Adolescent↗
PubMed1978

Ectopic lesion of schistosomiasis of the penis simulating an early carcinoma.

A case of ectopic lesion of Schistosoma haematobium of the penis with extensive tissue destruction, simulating an early carcinoma of the penis and almost resulting in an autoamputation of the crown of the penis, is presented. The penis was surgically repaired and the patient treated with ambilhar. In schistosoma endemic area, it is important to think of ectopic schistosoma lesion by such a presentation. Existing theories to explain the presence of schistosoma eggs in locations outside the portal-caval system were reviewed and another one was advanced: its being sexually transmitted.

Adult↗
PubMed1978

Keratosis circumscripta. A distinct dermatological entity or a variant of psoriasis?

45 cases of a dermatosis believed to be the same as those originally described by Schrank in 1963 among Nigerian children of Yoruba ethnic origin and named keratosis circumscripta by him are reviewed. All evidences point towards the fact that the dermatosis observed by us as well as those originally described by Schrank are a variant of psoriasis possibly modified by environmental factors. It has therefore been suggested that this dermatosis should not be regarded as a new dermatological entity, and that the original names should be modified. To reflect the original work done by Schrank as as well as the true clinical picture of this dermatosis, the nomenclature psoriasis circumscripta with palmo plantar keratosis is suggested.

Adolescent↗
PubMed1978

Contact allergic dermatitis "current topic in tropical dermatology".

Out of a total of 2,666 new dermatology patients, 128 (4.8%) were clinically diagnosed as allergic contact dermatitis. Of these, 107 (4%) reacted positively to different antigens in the patch-test. The commonest contact sensitizers among females were nickel and dyes. Among male patients, the commonest sensitizers were mecaptobenzol-thiazole, chrome and nickel. The incidence of occupational contact dermatitis among bricklayers, construction workers and builders were found to be low and the sensitization rate against chromate was 0.6%. There was no sensitization against cobalt and nickel in the group, however, the length of occupational contact with cement among these group was short. Allergic contact dermatitis is not as uncommon among the Nigeria populace as is generally believed. It seems to be on the increase especially with increase rate of industrialization.

Dermatitis, Atopic↗
PubMed1977

[Epidemiology of occupational disease among bricklayers in Nigeria. Effects of age and duration of contact].

Clinical and epidemiological investigations on 240 bricklayers in Nigeria show an incidence of 2,3% of cement-eczema, 2,0% of wear and tear dermatosis, and 2,8% of sensitivity against chrome. None of the examined showed a concomitant reaction to cobalt chloride. The workers with longest professional contact with cement showed the highest incidence of cement-eczema, and sensitivity against chrome. Workers of the lower age group had a higher alkali neutralization power of the skin than the older workers. The same tendency was noticed in the control tests. Generally, the African skin showed a higher alkali neutralization power than the white skin. The discussion tried to expand on the possible factors which could have influenced the observed rate of sensitization in Nigeria.

Age Factors↗
PubMedDate not supplied

Allergic manifestation in Nigerian asthmatics.

Intracutaneous and inhalative provocation tests performed on 185 asthmatic Nigerian patients and 50 control patients using indigenous antigen extracts as well as imported ones showed that moulds, house dust and D. farinae are the most common allergens responsible for the patients' asthmatic symptoms. Food allergy, though present, does not play a significant role among the patients. Pollinosis is not a common symptom among the patients although the Nigerian pollens are believed to possess antigenic properties. Environmental factors were thought to be responsible for the scarcity of pollen allergy in Nigeria. The importance of making use of indigenous antigen for allergy tests in stressed as this would reveal the true allergic state of the people.

Allergens↗