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Biomedical subjects

F Spagnolo

Publications and source records attributed to F Spagnolo.

6 recordsLinked to original sources

Mental rotation of tactual stimuli.

Three experiments involving different angular orientations of tactual shapes were performed. In experiment 1 subjects were timed as they made 'same-different' judgments about two successive rotated shapes. Results showed that no rotation effect is obtained, i.e., reaction times and error percentage do not increase linearly with rotation angle. The same negative results were found in experiment 2, in which subjects were similarly timed while they made mirror-image discriminations. In experiment 3 a single-stimulus paradigm was used and subjects were asked to decide if a rotated stimulus was a 'normal' or 'reversed' version. Reaction times increased linearly with angular departure from the vertical. Therefore, for tactual stimuli too, this study confirms previous results, which suggest that a mental rotation strategy only occurs if it is facilitated by both type of task and type of stimulus. Results also show a significant difference between hands, and between hands and type of response. Implied hemispheric differences are discussed.

Adult↗

HPLC analysis of commercial alkyl and aryl quaternary ammonium compounds used in organoclay type rheological additives.

Mixtures of aliphatic and aromatic "quats" can be qualitatively identified in a one step chromatographic run. After separation on a strong cation exchange column, the eluted components are detected using a UV and RI detector system in series. The quaternaries present in organoclays (e.g., BENTONE type products) can also be identified by prior destruction of the silicate with hydrofluoric acid followed by chromatography of the residual quat fluorides.

Aluminum Silicates↗

Rapid infrared determination of the potency of chlorinated bactericides.

A rapid infrared reflectance method for evaluating the germicidal potency of synthetic materials containing various amounts of two chlorinated bactericides was developed. The dimeric product 2,2'-methylenebis (4,6-dichlorophenol) exhibited a characteristic C=C skeletal inplane stretching infrared absorption band at 1,640 cm(-1). The monomeric 2,4-dichlorophenol precursor showed a characteristic absorption band at 1,579 cm(-1). These characteristic infrared absorptions may be used for analysis of the potency of the manufactured chlorinated bactericide. For a series of samples known to vary in dimer content, the micrograms per milliliter required for a 100% bacterial kill is first determined by a standard American Petroleum Institute method. Then the area ratio of the infrared absorption bands characteristic of the chlorinated bactericides is measured for each sample and plotted versus the microgram per milliliter required for 100% bacterial kill. The potency of subsequent samples is simply and rapidly determined by measuring this ratio from the infrared absorption curve and calculating micrograms per milliliter required for 100% kill from the calibration curve. Analysis time is approximately 1 hr compared to biocidal tests in current use requiring approximately a 1-month incubation period.

Alcohols↗