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F Spigariol

Publications and source records attributed to F Spigariol.

8 recordsLinked to original sources
PubMed1992

Computed tomography in predicting gall stone solubility: a prospective trial.

This prospective study was undertaken to evaluate the correlation between densitometric values of gall stones assessed by computed tomography and the success rate of litholytic therapy in 28 patients eligible for oral treatment. A densitometric study of the stones was performed in all patients before treatment. A cut off point of 60 Hounsfield units (HU) was chosen to divide the subjects into two groups--group 1, 14 patients with low density stones (less than 60 HU) and group 2, 14 patients with high density stones (greater than 60 HU). All patients were treated with ursodeoxycholic acid (8-10 mg/kg/day) for 12 months and followed up by ultrasound. In group 1, dissolution was complete in 50% of the patients and partial in a further 20%. In group 2 patients, complete dissolution was not observed but 33% showed partial dissolution. The number of patients with total dissolution at 12 months was significantly higher in group 1 compared with group 2 (p less than 0.02). These results suggest that computed tomography can be used to select patients with a better likelihood of successful stone dissolution after bile acid therapy.

Adult↗
PubMed1992

Computed tomography in the identification of gallstones likely to respond to UDCA.

An unusual case of a patient with two biliary stones of different densities that responded differently to oral litholytic treatment with ursodeoxycholic acid (UDCA) is reported. The findings confirm, in an unusual experimental model, that CT is useful in the selection of those stones which have a high probability of dissolution under treatment with oral bile acids.

Absorptiometry, Photon↗
PubMed1992

[Role of computerized tomography in the densitometric assessment of lithiasis of the gallbladder].

Radiolucent gallstones frequently contain significant calcium deposits. Their detection is important to select the patients to submit to medical gallstone dissolution. Since CT facilitates the identification of calcifications undetected at conventional radiologic procedures, 60 patients were studied with CT. All of them had US confirmation of cholelithiasis and in the whole of cases an X-ray examination of the right upper abdominal quadrant was performed (for the identification of radiopaque stones), together with oral cholecystography (to evaluate gallbladder function). CT attenuation values of the stones were measured and the patients subsequently divided into 2 groups; the threshold value was 50 HU: below it, the stones were considered hypo- or isodense (group I); above it, they were considered hyperdense (group II). Later on, 28 patients (14 from group I and 14 from group II) were selected for chemical dissolution with ursodeoxycholic acid over a 1-year period. US examinations were performed at 6 and 12 months. Seventy per cent of the patients in group I responded to treatment (50% with complete stone dissolution and 20% with partial dissolution), whereas no patient in group II had complete dissolution and only 30% had partial response.

Cholelithiasis↗
PubMed1991

Aspiration cytology and immunocytochemistry of sacral chordoma with liver metastases: a case report.

We present the cytologic features and immunocytochemical profile of a case of sacrococcygeal chordoma metastatic to the liver. Cytologic diagnosis was suspected from the aspiration biopsy smears of the primary sacrococcygeal tumor and confirmed by histology. Further aspirates failed to reveal diagnostic physaliferous cells, and only undifferentiated spindle cells were obtained. Chordoma may lack physaliferous cells: in such cases, immunocytochemistry studies can greatly facilitate the diagnosis. This study confirms the utility of immunocytochemistry in the differential diagnosis of chordoma and tumors with similar cytologic characteristics.

Aged↗
PubMed1990

Is computed tomography a reliable indicator of stone solubility?

This study was undertaken to ascertain whether CT evaluated stone densiometry, prior to treatment, is able to identify patients with high likelihood of success with litholisis. Eight patients with single radiolucent stone (less than 15 mm diameter) in a functioning gallbladder that showed no reduction in size after 12 months treatment with UDCA (10 mg/Kg/day) were submitted to CT scan to determine stone densitometry. Seven patients still had a radiolucent stone after therapy; six out of seven stones showed densitometric values over 50 Hounsfield units, which we considered the upper normal limit for stones consisting of cholesterol. CT can be a useful tool to identify patients at high risk for oral dissolution therapy failure.

Cholelithiasis↗
PubMed1988

[Role of computerized tomography and ultrasonic diagnosis in adrenal neoplasms with an adipose matrix].

Ten cases of adrenal lipomatous tumors discovered incidentally with ultrasounds (US) and computed tomography (CT) during examinations for the staging of malignant tumors are reported. Transparietal bioptic approach and surgery revealed three histologic diagnosis: non-functioning adenomas, lipomas and myelolipomas. Those findings confirmed that adrenal tumours with low density are mainly benign; but in neoplastic patients biopsy and surgery are still mandatory.

Adrenal Gland Neoplasms↗