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Biomedical subjects

F Stazi

Publications and source records attributed to F Stazi.

15 recordsLinked to original sources
PubMed1992

Effects of slow-release verapamil and nitrendipine on office and 24-hour ambulatory blood pressure in hypertensive patients.

The aim of the present study was to compare the effects of slow-release verapamil (V), 240 mg and nitrendipine (N), 20 mg, administered once daily, on office (OBP) and 24-h ambulatory blood pressure (ABP) in patients with mild-to-moderate hypertension. Twenty patients were entered into this open, randomized, two-group (V, N) parallel study. The study groups had similar age and sex distribution. The OBP (V, 155/103 +/- 19/8 mm Hg; N, 141/98 +/- 13/4 mm Hg), heart rate (HR) (V, 74 +/- 7 beats/min; N, 77 +/- 10 beats/min), daytime systolic ABP (V, 149 +/- 14 mm Hg; N, 147 +/- 13 mm Hg), and nighttime ABP of the two groups were not statistically different after a 2-week washout period. The daytime diastolic ABP (V, 99 +/- 6 mm Hg; N, 93 +/- 6 mm Hg) was slightly lower (p less than 0.05) in group N. Both the OBP (V, 136/90 +/- 19/9 mm Hg; N, 135/85 +/- 10/4 mm Hg) and daytime ABP (V, 132/85 +/- 14/4 mm Hg; N, 136/87 +/- 13/8 mm Hg) dropped in the two groups after 8 weeks of treatment. Nonparametric analysis did not show statistical differences between the groups in OBP and ABP percentage drop. There was no significant change in nighttime ABP, HR (V, 73 +/- 10 beats/min; N, 74 +/- 12 beats/min), ECG, and laboratory exams. We conclude that both verapamil SR and nitrendipine are effective in reducing blood pressure in hypertensive patients without altering the HR.

Adult↗
PubMed1992

[Infective endocarditis].

The authors underline the recent increase in the incidence of infective endocarditis (IE) involving the right side of the heart, because of instrumental procedures and, above all drug-addiction. They describe the epidemiology, congenital and acquired predisposing heart diseases, the most common portals of entry of the infective agents, etiology, pathogenesis, pathology, cardiac and extracardiac clinical manifestations and complications, clinical and instrumental diagnosis, medical and surgical therapy, prognosis and prevention of disease.

Anti-Bacterial Agents↗
PubMed1992

[Paget's disease].

The authors have observed several cases of Paget's disease in their Centre for the Study, Diagnosis and Therapy of Osteoporosis. They define this disease and describe the probable etiology by Paramyxoviruses, the macro- and microscopic anatomopathological changes, the clinical manifestations, the complications (that are sometimes deadly: sarcoma), the diagnostic resources and, finally, the latest therapeutic possibilities (combined calcitonin and diphosphonate) that are useful only in patients with pain or complications.

Adult↗
PubMed1991

[Orthostatic hypotension in the aged].

The authors consider the remarkable incidence and the important consequences of orthostatic hypotension in the elderly. They underline the etiologic importance of primary and secondary alterations of the autonomic nervous system and other concomitant causes. They illustrate the pathophysiologic mechanisms and specify how to arrive at the correct diagnosis. Finally they recommend to use drugs only after the failure of behavioral and physiatric measures.

Age Factors↗
PubMed1991

[The cardiovascular system and antidepressive drugs].

The authors consider the ever-increasing number of depressed patients, related to the stress of modern life and to the prolongation of life span. They stress that these patients are often cardiopathic or impaired by the senile heart. Finally they illustrate the cardiovascular effects of antidepressant drugs and how to avoid them.

Aged↗
PubMed1991

[Aneurysm of the abdominal aorta. Description of a case].

Having recalled the insidious onset, etiopathogenesis, incidence, clinical and instrumental diagnosis, and the very severe prognosis of abdominal aortic aneurysm, as well as the excellent results obtained by elective surgery, the authors describe a case they had occasion to observe and in which sudden rupture of the aneurysm was fatal.

Aged↗
PubMed1991

[Cardiac risk in noncardiac surgery].

After recalling cardiac disorders and the cardiac risk of non cardiac surgery, the authors illustrate the methods for evaluating clinical risk in individual patients, the instrumental procedures appropriate for the diagnosis of ventricular dysfunction or myocardial ischemia which are responsible for the majority of cardiac complications during surgery. Finally, they describe alternative therapies for high-risk patients.

Adult↗
PubMed1990

[Sacrococcygeal chordoma. A case report].

The authors describe the diagnosis of a rare neoplasm, a sacrococcygeal chordoma, which was suspected in view of compressive symptoms and diagnosed with the aid of endoscopic and x-ray methods (barium enema and CT). Diagnosis was confirmed at surgery.

Biopsy↗
PubMed1990

[Tuberculosis: a disease that is difficult to eradicate. Description of a case].

The authors stress the recent increase of tuberculosis, especially in high-risk areas and populations. They illustrate the changes the disease has undergone lately, also with reference to a case they had occasion to observe. They describe 9-month and 6-month treatment schemes as well as the drugs that can be applied in cases of drug resistance which is rather frequent in AIDS patients.

Acquired Immunodeficiency Syndrome↗
PubMed1990

[Carcinoma of the pancreas and description of 5 cases].

Having reviewed the frequency of pancreatic cancer, its symptomatological insidiosity, the risk factors, the present excellent diagnostic possibilities, the surgical techniques, which are unfortunately radical only in 30% of the cases, the potentialities related to the recent discovery of sex-hormone receptors in the tumor, the authors underline the necessity of an early diagnosis, considering carefully the vague, but precious, initial symptoms.

Aged↗
PubMed1989

[Osteoporosis: a silent thief].

Having stressed the often disregarded social importance of osteoporosis and listed the risk factors, the authors illustrate the classification, etiopathogenesis, paucity of symptoms and the most valuable diagnostic resources, and discuss present therapeutic possibilities, while stressing the fact that, as in many other situations, prevention remains the best policy.

Bone Resorption↗
PubMed1989

[Therapy of cardiac arrhythmias in the aged].

Having reviewed the pathophysiologic changes of old age and their consequences in terms of pharmacokinetics and pharmacodynamics, the authors indicate the correct choice and the proper use of antiarrhythmic medication in these.

Age Factors↗