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Biomedical subjects

F Stivala

Publications and source records attributed to F Stivala.

43 records · Page 3Linked to original sources

[Protection against experimental infections in mice by an oral vaccine and its combined role when administered with antibiotics].

Immunomodulator with significantly modify the immunologic response of the host. The AA. studied the immunologic profile of an oral vaccine to protect the experimental infection in mice and its effect when it was administered with antibiotics. The mice infected with S. enteritidis were protected by the vaccine administered. Also in the group of mice treated with a vaccine and antibiotic combination, the mortality rate was lower than in the untreated groups.

Administration, Oral↗

[Immunologic characteristics of a polyvalent vaccine].

A lot of bacterial vaccines show a very interesting immunostimulating profile. The AA. studied the effects of a polyvalent vaccine on the phagocytosis, on the cellular immunity and on the IgA production. They also investigated its capacity to reactivate the response to the C tetani toxin (Booster effect), both "in vitro" and in human volunteers. The results show a significant improvement in the immunity response to specific and aspecific stimuli.

Administration, Oral↗

[Changes in the membrane receptors of lymphocyte populations during immunization].

A population of splenic lymphocytes has been studied as well as their surface antibodies and their affinity for antigen in different days and periods of immunization. Fractionation of a specific population of lymphocytes having an affinity for antigens coated on glass beads were accomplished. The other aspecific population did not bind ot the glass beads and was not retained on the column. During the primary immuno-response the number of lymphocytic cells with surface antibodies specific for antigen was higher than in the booster response: in secondary response only the total number of antibody forming-cells increases while the number of lymphocytes with surface antibodies is constant. The authors suppose that the surface of spleen lymphocytes is modificated in different way at different time, by immunizing antigen.

Animals↗

[Immunologic study on patients with head and neck cancer treated with thymopentin associated with surgery, chemotherapy and radiotherapy].

Patients with H&N tumours treated with surgery, chemo- and radiotherapy also underwent an immunologic therapy with timopentina to evaluate clinic and immunologic efficacy during a 1-year follow-up. Twenty-five patients were recorded in this study divided at random into two groups. In group A the patients were administered timopentina (50 mg/3 times per week/6 weeks) subcutaneously in 4 o 5 cycles during the year. Group B were not administered timopentina. The immunologic state was assessed through investigation of the following: Evaluation of PBL and their T and B cell subpopulations Phagocytosis and blastigenesis Surface receptor and soluble receptor of IL2 NK activity IL1 production. The immunologic values of the two groups were correlated against a control group of twenty non-neoplastic patients. Our study revealed a better immunologic conditions at the end of follow-up in patients treated with timopentina compared to the other patients.

Combined Modality Therapy↗