PubMed Health⌕ Search

Biomedical subjects

F Strollo

Publications and source records attributed to F Strollo.

45 records · Page 3Linked to original sources
PubMed1981

[Behavior of triiodothyronine, tetraiodothyronine and thyrotropin during the TRH test].

Much confusion seems to exist on the timing and intensity of thyroid hormones (T4 and T3) response to TRH. As a first approach to the problem, the Authors performed TRH test in 5 healthy women. TSH showed a significant increase immediately after the TRH injection and kept high until the 90th minute. T3 decreased at first-still not significantly--then increased steadily and at 60 min it reached values significantly higher than the basal ones. Some increase was seen for T4 too, but it did not show to be statistically significant within 180 minutes. The Authors give revelance to the significance of precious (60 min) T3 increase in such a small casuistry.

Adult↗
PubMed1981

[Preliminary observations on the existing relationship between plasma levels of prolactin and hypophyseal reserves of FSH and LH in the male].

PRL plasma levels and FSH and LH pituitary reserve were tested in ten apparently healthy male subjects. A good correlation was found between PRL on one hand and FSH plasma levels (p less than 0,05), LH plasma levels (p less than 0,01) and FSH pituitary reserve (p less than 0,01) on the other hand. This seems to support the current hypothesis that prolactin may cause a progressive clinically latent impairment in the spermatogenetic function of the testis. Further evidence is needed.

Adult↗
PubMed1981

[Relationship between benign breast cancer and plasma levels of prolactin].

Prolactin (PRL) plasma levels were measured in the follicular phase of the cycle in 75 normally menstruating women divided into three groups: group I was normal (n. = 39), group II showed benign breast disease (n. = 26), group III hyperandrogenism (n. = 10). PRL levels were higher (670,8 +/- 61,2 microunits/ml) in the second group than in the first (216,0 +/- 12,0 microunits/ml; p less than 0,001) and in the third group (426,0 +/- 75,2 microunits/ml; p less than 0,02). Two mechanisms are hypothesized as a possible explanation for the results: a) hyperprolactinemia primarily alters progesterone/oestradiol ratio which secondarily initiates benign breast disease, or b) relative hyperestrogenism causes an increase in PRL plasma levels, which, in turn, interact with oestradiol to give mammary gland hypertrophy. Further studies are needed in order to elucidate the problem.

Adolescent↗
PubMed1981

[Changes in blood prolactin in relation to the menstrual cycle].

Scientists are in general agreement on the hypothesis of a prolactin surge at midcycle. In order to test this hypothesis the Authors measured radioimmunoassayable circulating prolactin in the follicular phase and at midcycle in 15 normally menstruating health women. Due to the well known individual variability, mean prolactin values showed statistically poor differences in the two phases of the cycle. Though, a very good positive correlation (r = 0.72, p less than 0.01) was shown when individual follicular values were plotted against the corresponding midcycle values. The Authors conclude that at midcycle prolactin increases significantly and discuss physiological significance of this phenomenon.

Adult↗
PubMed1981

[Age-dependent changes in epitestosterone urinary excretion in man].

Previous studies carried out by the Authors had shown an increased urinary excretion of epitestosterone, a poorly active androgen mostly believed to be of adrenal origin, after HCG administration to presenescent and aging subjects. Purpose of this study was to ascertain whether or not this held in the young too. Testosterone excretion sharply decreased after the age of 60 (P less than 0,001); 17 KS on the other hand, decreased progressively in such a way that the aging group showed significantly lower (p less than 0,05) excretion rates than the only young-adult group. ET excretion decreased steadily but not significantly with age. ET showed a very good correlation to T (p less than 0,01) both under basal and poststimulatory conditions in each of the three age groups. ET percent increase showed a good correlation (p less than 0,01) to T percent increase only in young-adult and presenescent people, not in the elderly. Poor was the correlation between ET percent increase and 17 KS percent increase. Thus ET excretion pattern showed to be somewhat different from that of T and very different from that of 17 KS. As a conclusion (a) epitestosterone excretion rate seems to decrease steadily but not significantly with age; (b) epitestosterone probably is not mainly secreted by the adrenal gland. A major source may be the testis, but liver, prostate and blood red cells metabolism are not definitely ruled out.

17-Ketosteroids↗
PubMed1981

[Extrarenal excretion of epitestosterone in the adult male].

Twentyfour hour-urinary 17-oxo-steroids (17 KS), epitestosterone (ET) and testosterone (T) were measured before and after a 5-day-HCG-stimulation test performed in 65 healthy male volunteers aged 30 to 76 years. Subjects whose basal urinary T was higher than average physiological values showed a lower increase (p less than 0,001) in ET excretion rate after HCG stimulation than the rest of the casuistry. Neither T nor 17 KS increase after HCG stimulation showed any significant differences in the two subgroups. As ET behaves differently as compared both to the typical testicular androgen, and to the testicular-adrenal metabolites, the adrenal glands may not be the only nor even the main source of ET in the urine of healthy men.

17-Ketosteroids↗
PubMed1981

[Verification of 2 fundamental types of kalemic curves during glucose tolerance tests].

The authors have carried out statistical analysis of serum K+ decrease during OGTT test. Two kinds of K+ curves were distinguished: "one way" and "undulating". The latter are characterized by: faster starting K+ decrease (p less than 0.05), faster speed slowing down (p less than 0,005), lower starting serum K+ (p less than 0,02), precocious sign-inversion of decrease-speed value, serum K+ level before rebound lower than final K+ level in the "one way" curves. Clinical significance of this is due to the fact that in "one way" curves, low K+ levels are kept longer, presumably causing diffuse tissue damage.

Adolescent↗
PubMedDate not supplied

Harmonized Italian version of the Aging Males' Symptoms scale.

INTRODUCTION: The interest in clinical investigations in health-related quality of life (HRQoL) of aging men has increased over recent years, particularly in the context of partial androgen deficiency. The aim of this paper is to inform the scientific community about a harmonized Italian Aging Males' Symptoms (AMS) scale. METHODS: There were two slightly different Italian AMS scales, which both underwent an up-to-date linguistic & cultural translation process, i.e., were both valid to be applied in clinical research. However, there are potential long-term problems associated with having two Italian language versions of the scale in the same country. Therefore, an ad hoc committee of key persons related to both versions met with the scale's developer, to create a harmonized single Italian AMS. RESULTS: The harmonization meeting came up with a consensus item-by-item and the new Italian reference scale was agreed upon. It was decided that this scale should be published to avoid any confusion among future users. CONCLUSION: The Italian AMS scale published in this paper should be used for future clinical and other research.

Aged↗