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Biomedical subjects

F T Given

Publications and source records attributed to F T Given.

32 records · Page 2Linked to original sources
PubMed1984

Normal pregnancy and delivery following conservative surgery and chemotherapy for ovarian endodermal sinus tumor.

Management of younger patients with early stage ovarian endodermal sinus tumor who desire to have children can be a challenging problem. However, after an adequate and thorough staging procedure for the patient's tumor status, a Stage Iai endodermal sinus tumor may be treated with conservative surgery only, followed by chemotherapy. Successful pregnancy and delivery following unilateral adnexectomy and chemotherapy for ovarian endodermal sinus tumor have been reported only once [J. P. Forney, Obstet. Gynecol. 52, 360 (1977)]; the second reported case is presented here. It should be pointed out that strict follow-up and reliability of the patient are mandatory for such conservative therapy.

Adult↗
PubMed1983

The use of Laminaria japonica in intracavitary radiation therapy when anesthesia is contraindicated.

Laminaria tents have been used to dilate the cervix for interruption of pregnancy and other intrauterine procedures. Their use is presented in 5 patients with cervical and endometrial carcinoma where general anesthesia was contraindicated. Cervical dilation was sufficient with a single Laminaria to carry out intrauterine and intravaginal instrumentation for radiation therapy with no local or general anesthesia.

Adenocarcinoma↗
PubMed1978

Preoperative radiation therapy in the management of squamous cell carcinoma of the vulva: preliminary report.

Fourteen cases of squamous cell carcinoma of the vulva treated preoperatively by use of cobalt-60 irradiation directed to the vulva and inguinal areas are reviewed. Toral dose varied from 3,600 to 5,500 rads according to reaction and tolerance. No treatments had to be interrupted due to excessive radiation effects. Surgical procedures were performed six weeks after irradiation. Histologic investigation of the surgical specimen showed no sign of tumor in five cases, almost complete regression in three, and a substantial reduction of the lesion in the remainder of the cases. In situ lesions surrounding the invasive tumors were cleared in three cases. Lymph node involvement was found in only two patients, one of whom did not receive preoperative radiation to in inguinal areas. Only one local recurrence was encountered and this was in the abdominal skin outside of the irradiated area. The healing process does not seem to be impaired after radiation treatment in spite of the fact that in many patients a very extensive type of surgical procedure was carried out.

Aged↗
PubMed1978

Cooperative approach to the treatment of cervical cancer.

This study covers 20 years' experience in the treatment of carcinoma of the cervix. Improved results and a decreased rate of major complications are seen as a result of a cooperative approach in treatment planning and careful dosimetry. Comparisons are made with large treatment centers as well as with national survival rates. Preliminary results with improved radiotherapeutic techniques continue to show improvement in survival rates.

Family Practice↗
PubMedDate not supplied

Granuloma inguinale: a case report.

A 20-year-old woman developed bleeding because of a painless genital ulcer. The diagnosis of granuloma inguinale was proven by showing the presence of Donovan bodies in a biopsy of the lesion. Treatment with tetracycline was successful when given in adequate dosage. Granuloma inguinale, although rare, should be considered in the differential diagnosis of patients with asymptomatic genital ulcers. Multiple biopsies may have to be done and stained with fresh Giemsa to prove the diagnosis, as in this case.

Adult↗