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F T Hoaglund

Publications and source records attributed to F T Hoaglund.

30 records · Page 2Linked to original sources

Diagnosis of osteoarthritis: the value of laboratory tests.

Osteoarthritis by definition involves a progressive degeneration in one or many synovial joints and has a multifaceted etiology. The limitation of pathologic responses to an initial insult minimizes the value of microscopic examination of the tissues long after the original injury. The cornerstone of diagnosis has been the plane film x-ray examination, which allows the study and comparison of macroscopic changes that are common to osteoarthritis and aids in diagnosing other causes of arthritis. Synovial fluid analysis in doubtful diagnoses is useful in ruling out specific arthritides such as infection or crystal induced arthritis, or in pinpointing inflammation as a factor in the individual case. Synovial fluid studies are especially important in allowing recognition of conditions in which appropriate treatment can prevent secondary osteoarthritis, e.g., sepsis. This technique may also be necessary to rule out sepsis before implant joint reconstitution.

Biopsy

Fat macroglobulemia caused by fractures or total hip replacement.

The numbers of fat macroglobules in peripheral venous blood were recorded for 136 prospectively studied patients with fractures of the pelvis, femur, or tibia. Groups of healthy volunteers and patients undergoing total hip replacement or abdominal surgery served as controls. The highest incidence of fat macroglobulemia occurred in patients with fractures of the femur who also had these clinical signs: petechiae, hypoxia, and depression of the central nervous system. The peak incidence occurred within the first eight hours after fracture. The over-all incidence of fat macroglobulemia in the other surgical patients was roughly equivalent to that in the fracture patients.

Adult

Osteoarthritis.

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Acromegaly

The pattern of deep-vein thrombosis and clinical course of a group of Hong Kong Chinese patients following hip surgery for fracture of the proximal femur.

In a prospective study of deep-vein thrombosis following hip surgery for fractures of the proximal femur, 45 Hong Kong Chinese patients were examined by bilateral functional ascending phlebography 7 to 28 days postfracture and 5 to 15 days post-surgery. In 14 patients, the phlebography was repeated 10 to 32 days later. The patients were followed for 27 to 32 months. The phlebographic pattern of the venous thrombi were analyzed, and the clinical course of the patients was presented. Despite the fact that the overall incidence of deep-vein thrombosis in this group of Chinese patients was similar to that reported in the West, clinical pulmonary embolism was not observed. The study suggested a difference in the distribution, pattern and probably the natural history of the venous thrombi among the Chinese when compared with the Western series.

Adult

Pulmonary thromboembolism and venous thrombosis in the Chinese.

In 3,876 autopsies performed between 1964 and 1974 in adult Hong Kong Chinese, the incidence of pulmonary thromboembolism was 0.75%. In a prospective study of 70 autopsies, the right lungs were inflated, fixed, slab-sectioned, and studied for pulmonary thromboembolism. Twenty-seven per cent had evidence of pulmonary thromboembolism, although in only one case was the lesion the cause of death. In another 62 autopsies, routine dissection of pelvic and both lower extremity veins revealed that 18% had evidence of thrombosis. Eighty-three per cent of these had pulmonary thromboembolism; in 3 of these 62 cases (5%) pulmonary thromboembolism was the cause of death. Massive pulmonary thromboembolism in the Hong Kong Chinese is much less frequent than in Caucasians. The finding of many small asymptomatic pulmonary thromboemboli in both racial groups suggests that pulmonary circulation performs a physiologic filtering function. The rarity of massive clots in the Chinese warrants further investigation and special attention to biomechanics of thrombosis formation and detachment.

Adolescent