PubMed Health⌕ Search

Biomedical subjects

F Taguchi

Publications and source records attributed to F Taguchi.

At least 181 records · Page 10Linked to original sources
PubMed1976

[Immunization of the nude mouse against mouse hepatitis virus through the transfer of sensitized lymphocytes].

Nude (nu/nu) mice failed to resist to virulent mouse hepatitis virus (MHV) infection after vaccination with inactivated virus. Resistance was induced in nu/nu mice by the transfer of spleen cells from heterozygous haired (nu/ +) mice concomitantly with the vaccination, and the effect was more remarkable with spleen cells from immunized nu/ + mice. Antibody was demonstrable in nu/nu mice having received nu/ + cells and survived challenge infection.

Animals↗
PubMedDate not supplied

Growth inhibition of herpes simplex virus-1 in the cells expressing abundant 2.0-kilobase latency-associated transcripts.

To elucidate the function of the latency-associated transcript (LAT) of herpes simplex virus type 1 (HSV-1) in productive infection and latency, we established a cell line stably expressing LAT (V24 cells). V24 cells expressed 2.0-kilobase RNA that corresponds to the major species of LAT in mouse and human sensory ganglia. When the cells were infected with HSV-1 at a low multiplicity of infection, the amount of the progeny virus was much smaller in V24 cells than in a control cell line not expressing LAT. Inefficient growth of HSV-1 in V24 cells was also observed when viral replication was initiated by transfection with viral DNA.

Animals↗