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F Tarhan

Publications and source records attributed to F Tarhan.

8 recordsLinked to original sources

Effects of unilateral testicular torsion on the blood flow of contralateral testis--an experimental study on dogs.

The effects of unilateral testicular torsion on the blood flow of the contralateral testis were investigated. Fourteen adult male dogs were recruited. Seven dogs underwent unilateral testicular torsion of 4 h duration, and the other seven dogs had a control operation. Testicular blood flow was determined by colour Doppler ultrasonography before and after the testicular torsion. Bilateral orchidectomy was performed at the end of the study and histopathological changes were evaluated. Values of peak systolic velocity, end diastolic velocity, and resistive index were not statistically significant between ipsilateral and contralateral testes in the study group (p > 0.05). On comparison with the control group, blood flow in the contralateral testes showed no statistically significant difference (p > 0.05). Oedema and congestion were seen on ipsilateral testes in the study group. No histopathological changes were noted on the contralateral testes. Minimal oedema and congestion secondary to manipulation were found in the control operation testes. We conclude that unilateral testicular torsion does not decrease contralateral testicular blood flow as shown by colour Doppler ultrasonography.

Animals↗

Cavernous oxygen tension in the patients with erectile dysfunction.

We designed a study consisting of 27 consecutive patients with erectile dysfunction in order to evaluate the role of cavernous oxygen tension. Patients were completely evaluated by history, physical examination, multiple blood analyses, serum testosterone level measurements, papaverine test, color duplex sonography and dynamic infusion cavernosometry-cavernosography. Blood gas samples were obtained from femoral artery and corpus cavernosum before drug injection and also from corpus cavernosum at 5, 10, 20, 30, 40 min following drug injection. Aetiologic classification of erectile dysfunction in our patients was as follows: psychogenic in 8, cavernosal failure in 14 and arterial disease in 5 cases. At flaccidity, no significant differences were found in the mean pO2, sO2, pCO2 and pH values of patient groups. After injection of intracavernous papaverine, results of the cavernous pO2 (P < 0.05), sO2 (P < 0.05) levels were found to be statistically significantly different between patients with vascular and psychogenic erectile dysfunction. Analysis of maximal cavernosal oxygen tension and PSV revealed statistically significant correlation (r = 0.66, P < 0.001). The results of this study suggest that changes in arterial and cavernosal pO2 and sO2 values may be contributing factors or co-factors in erectile failure.

Adult↗

An enigma: contralateral effects of experimental unilateral testicular torsion.

To investigate the effects of unilateral testicular torsion on both testes, we studied 4 groups of adult male New Zealand rabbits using sham operation, torsion and detorsion after one or eight hours and permanent torsion. Bilateral orchiectomy was performed 9 weeks after the operation, and testicular weights, Johnsen scores, quantitative analyses, tubular diameters were calculated and histopathologic diagnosis was determined. Testicular weights, Johnsen scores, spermatid counts and tubular diameters were all decreased in torsioned testes depending on the duration of torsion. The contralateral testes showed no significant change in any of the study groups when compared with the control group.

Animals↗

Effect of intracavernosal sodium nitroprusside in impotence.

Recent studies have shown an important role for nitric oxide (NO) in cavernous smooth muscle relaxation. In this study the intracavernosal effects of the NO donor sodium nitroprusside (SNP) were investigated in 32 patients with erectile dysfunction. Erectile response and penile blood flow were investigated following intracavernosal administration of 360 micrograms SNP and 60 mg papaverine for diagnostic purposes. In all of 32 patients the erectile response to SNP was not better than that to papaverine. Haemodynamic evaluation of the deep penile arteries was carried out by colour duplex Doppler sonography after administration of SNP and papaverine. No differences in peak flow velocities were measured, but the increases in diameter and end-diastolic velocities were higher after SNP than after papaverine. Our data suggest that the NO donor SNP is not a new alternative agent for diagnosis and treatment of impotence.

Adult↗

Oxytocin-induced contractions of the rabbit corpus cavernosum.

The contractile effect of oxytocin on isolated rabbit corpus cavernosum strips was investigated. Concentration-response curves to oxytocin and phenylephrine were obtained. Oxytocin repetitively induced concentration-dependent contractions in the corpus cavernosum strips. The maximal contractile response to oxytocin was in amplitude 39.4 +/- 9.1% of that to phenylephrine. The slopes of the concentration-response curves, the amplitude of the maximal contractile effects, and the pD2 values of oxytocin obtained in endothelium-denuded strips were not significantly different from those of intact preparations. The results of this study demonstrated that oxytocin contracts the rabbit corpus cavernosum, but the endothelium does not contribute to this effect. Since oxytocin is less efficacious than phenylephrine, it seems unlikely that this hormone can serve as an alternative in the treatment of prolonged penile erections.

Animals↗

[A case of a schistosomal bladder polyp].

A 67 year old patient who had transürethral resection because of previous diagnosis of bladder tumor and schistosomal polyp was detected on the histopathologic and the microbiologic examinations were presented.

Aged↗