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Biomedical subjects

F Tarr

Publications and source records attributed to F Tarr.

16 recordsLinked to original sources
PubMed2000

[Alteration of nitric oxide production during arterial myocardial revascularization using extracorporeal circulation. Quantitative measurement of EDNO production by the internal mammary artery bypass graft].

Authors measured the concentration of stable metabolite (NO2: nitrite) of EDNO (endothelium derived nitric oxide) in the internal mammary artery (IMA) bypass graft with the help of a previously reported method (measurement of effective blood flow capacity of the IMA graft in the coronary sinus). Nitrite level in the systemic circulation prior to extracorporeal circulation (ECC)--(68.1 +/- 6.7 mumol/l) was measured, as well as nitrite concentration in the coronary circulation before and after construction of the IMA bypass graft (62.1 +/- 4.19 mumol/l and 50.26 +/- 4.0 mumol/l respectively). Furthermore, nitrite level in the IMA graft free cut end flow was also determined (64.3 +/- 5.9 mumol/l). These data compared to the nitrite levels in the normal plasma (48.1 +/- 5.9 mumol/l) were found to be higher (p = 0.1, ns.), possibly due to the enhanced EDNO production induced by total heparinization. The nitrite concentration in the IMA free cut end flow is similar or slightly higher than that of the native coronary circulation, however, after IMA bypass construction a relative reduction could be measured in the coronary sinus. Authors believe, that this may be related to the reduction of basal EDNO production caused by supernormal pO2 (215 +/- 19 mmHg) during ECC.

Adult↗
PubMed1999

[Clinical experience with surgical management of atrial myxoma].

Clinical data (symptoms, diagnostic tools, surgical and histological findings, postoperative course and present status) of 26 patients with cardiac myxomas were reviewed. All myxomas were of left atrial localization. The diagnosis was confirmed by cardiac catheterization and angiography (until late seventies) and echocardiography. The delay between diagnosis and surgical management was minimalized. There was one early postoperative death. During follow-up period, one patient died, most patients live without symptoms. No recurrences have been found by echocardiographic follow-up examinations. Late consequences can be revealed by careful follow-up and regular echocardiographic studies.

Adult↗
PubMed1997

Urgent coronary artery revascularization with different arteries.

Authors present the case report of a young man with advanced coronary artery disease of the left main trunk, and the large tributaries of the left coronary system, leading to sudden onset of many ventricular fibrillation, associated with unconsciousness requiring several reanimation. The condition was treated with coronary artery surgery with the use of three different arterial conduits (right radial artery, right gastroepiploic artery as free grafts and the left internal mammary artery in situ) with an additional saphenous vein bypass graft. Details of surgical activity as well as the documents of the early postoperative course and of the 1 month follow-up are described.

Adult↗
PubMed1996

[Emergency coronary revascularization using various arteries].

Authors present the case report of a young man with advanced coronary artery disease of the left main trunk and the big branches of the left coronary system leading to sudden onset of many ventricular fibrillations associated with unconsciousness requiring several reanimations. The condition was treated with coronary artery surgery with the usage of three different arterial conduits (right radial artery, right gastroepiploic artery as free grafts and the left internal mammary artery in situ) with an additional saphenous vein bypass graft. Details of surgical procedures as well as the documents of the early postoperative course and of the 1 month follow up are given.

Adult↗
PubMed1995

[Incidence of perioperative myocardial necrosis in the course of coronary bypass surgery].

Authors report an analysis of 101 patients' perioperative data in the view of myocardial necrosis development. Perioperative myocardial infarction is defined as simultaneous detection of new Q wave, and myocardial specific enzyme release with concomitant, transient pump failure. They conclude by the data of patients operated upon, that the quoted criteria were detected simultaneously in 9 patients. Other 7 patients had CK-MB levels of pathological level, but without evidences of any other myocardial infarction criteria. Minimal myocardial mass loss as a sort of terminology is introduced, which is obviously not considered as equal to true myocardial infarction.

Adult↗
PubMed1994

Stable myocardial performance at clamped aorta based solely on the internal mammary artery graft flow: a functional test.

Authors report their experiences with arterial revascularization of the heart using the internal mammary artery (IMA). A method of intraoperative measurement of the free cut end and the effective graft flow of the IMA after meticulous anatomical dissection is described. Free cut end IMA flow was measured both at systemic and extracorporeal pump perfusion pressure and was found as 145+/-26 ml/min and 135+/-16 ml, respectively. A method of measurement of the effective IMA graft flow was introduced and described. An attempt was made to identify factors leading to stable myocardial performance based only on the IMA graft flow just prior to declamping the aorta. The phenomenon is considered as a reliable functional test regarding precise IMA harvesting, anastomosis construction and IMA graft flow capacity.

Adult↗
PubMed1993

[Simultaneous surgery for trivalvular and ischemic heart disease as well as calcification of the ascending aorta].

Authors present a case report about the surgical management of trivalvular and ischemic heart disease. The strategy of surgery: venous, arterial revascularisation, valve replacements, valvular plasty is discussed in conjunction with the management of the calcified ascending aorta. The details of the procedure and data of the early follow up period (6 months) are presented.

Aorta↗
PubMed1992

[Surgical treatment of ischemic heart disease and unstable angina pectoris caused by intramyocardial descending coronary artery in a young patient].

Authors present a case report about the surgical management of a genetically predisposed ischemic heart disease occurred in young age with rare anatomical variation causing unstable angina pectoris. Besides the description the type of surgery, emphasis is made on the importance of whole scale cardiological investigations and--as in the described case--on the role of nearly ideal cooperation between the cardiologist and heart surgeon, which finally could prevent a larger size of myocardial infarction to occur.

Adult↗
PubMed1991

[Arterial revascularization of the heart and intraoperative balloon angioplasty].

Authors report a combined method currently introduced in their practice in surgical treatment of ischemic heart disease. Besides the solely arterial revascularisation of the heart, successful intraoperative balloon dilatation of the recipient LAD stenosis was carried out. Main steps of the method's history, indication and the required tools are described. Through a case report on the ground of experiences reported in the literature they stand for and the use of the method.

Angioplasty, Balloon↗
PubMed1991

[Coronary revascularization in post-infarction patients].

Authors report the type of revascularization, the result of noninvasive and invasive investigations carried out 6-9 months after surgery, improvement of functional status of 56 postinfarction patients with recurrent angina pectoris. They conclude, that recoronarography performed in 12 patients revealed diminished patency rate compared to the estimated predictive one, especially in those, where complete revascularization was considered to have been carried out. Ejection fraction, wall motion score by ventriculography and echocardiography did not seem to improve significantly. However Dipyridamol Thallium scintigraphy showed marked improvement in perfusion in all cases. NYHA functional status has noticeably improved in the reexamined patients.

Echocardiography↗
PubMed1991

Coronary artery revascularization after myocardial infarction.

Authors report on the revascularization resulted by noninvasive and invasive interferences carried out 6-9 months after surgery and on the improvement of functional status of 56 postinfarction patients with recurrent angina pectoris. They conclude that recoronarography performed in 12 patients revealed diminished patency rate as compared to the estimated rate, especially in those cases, where complete revascularization was considered to have been carried out. Ejection fraction, wall motion score by ventriculography and echocardiography did not seem to improve significantly. However Dipyridamole Thallium scintigraphy showed marked improvement in perfusion in all cases. NYHA functional status noticeably improved in the re-examined patients.

Adult↗
PubMed1990

[Surgical management of aneurysm of the ascending aorta associated with aortic valve insufficiency].

Out of 318 aortic valve replacements performed between July 1, 1984 and June 30, 1989, aneurysm of the ascending aorta was found in 17 cases. In 7 of these cases employment of conduit was required due to the dimension of the aneurysm. In 5 cases they performed Bentall procedure: aortic valve replacement combined with conduit of the ascending aorta with the replantation of the coronaries. Based on the data of the literature and the acceptable early and late results of their own they conclude, that in case of simultaneous occurrence of aortic valve disease and aneurysm of the ascending aorta the Bentalll procedure is the method of choice.

Adult↗
PubMedDate not supplied

Endocavital cooling in intraoperative myocardial protection during extracorporeal circulation.

The possible protective effect of endocavital cooling with a balloon left ventricular vent was studied by post cross clamp time rhythm, ECG, DC shock need, dynamics of temperature changes in the interventricular septum, and positive inotropic support requirement in 60 extracorporeal operations (18 aortic valve replacement, 26 aortocoronary bypass and 16 combined procedures) performed by the same team of surgeons with an identical technique and anaesthetic protocol. The results were compared to the data of 60 similar procedures carried out earlier by the same team but without the balloon technique. We conclude that endocavital cooling may have certain additive effects to chemical cardioplegia, especially in cases with left ventricular hypertrophy, multiple coronary stenoses, and in combined procedures.

Aortic Valve↗
PubMedDate not supplied

Coronary artery bypass surgery on the beating heart.

Authors report their experiences with coronary artery bypass surgery without cardiopulmonary bypass. Between January 1993 and June 1995, 151 patients were operated upon by the same surgeon for ischaemic heart disease (IHD); 7 were of them without extracorporeal circulation (ECC). Patients were selected for the procedure on the following criteria: (1) symptomatic patient with proximally occluded, anteriorly located, major subepicardial artery(ies) unsuitable for, or after failed, PTCA; (2) presence of associated disease (like hypertension, diabetes mellitus, chronic obstructive pulmonary disease) enhancing a possible deleterious effect of cardiopulmonary bypass; (3) favourable response to beta-blocking agent pretreatment without side effects. Seven patients' perioperative data (white cell count, platelet count, whole plasma protein level, chest drainage, CK-MB release--incidence of perioperative myocardial mess loss--and days spent in the intensive care unit /ICU/) are compared to the corresponding data of patients with comparable pathology operated on with ECC. No blood transfusion was required, nor perioperative myocardial necrosis occurred. The patients operated on without ECC spent only 24 hours in the ICU, and the clinical check-up after 1-24 months revealed conditions free from angina pectoris. The patient's quality of life improved.

Aged↗