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Biomedical subjects

F Tennant

Publications and source records attributed to F Tennant.

26 records · Page 2Linked to original sources

Ultrasound needle guidance for amniocentesis in pregnancies with low amniotic fluid.

In six pregnancies accompanied by oligohydramnios (three cases) or decreased amniotic fluid and maternal obesity (three cases), needles specifically designed for use with ultrasound were successfully utilized in combination with real-time ultrasound guidance for amniocentesis. There was successful fluid retrieval in all six, with two requiring more than one needle pass. All three cases accompanied by oligohydramnios later resulted in fetal death. In the three cases accompanied by decreased amniotic fluid and maternal obesity, the amniocentesis results were helpful in ensuring the existence of a normal pregnancy. A specially designed ultrasound needle used in combination with a real-time guidance system is helpful in the performance of difficult amniocentesis.

Amniocentesis↗

Propoxyphene form maintenance treatment of narcotic addiction.

Two studies compared propoxyphene napsylate (Darvon-N) with methadone hydrochloride as maintenance treatment for narcotic addicts. Most measures indicated that methadone was more effective than propoxyphene as a maintenance drug. Patients receiving propoxyphene reported more withdrawal-related symptoms early in treatment, tended to drop out sooner than patients receiving methadone, and were more likely to abuse heroin. Nevertheless, follow-up interviews at one and six months after treatment indicated no between-group differences in adjustment.

Adult↗

Medicinal use of hypodermic needles in an addict patient population.

Narcotic addicts may become so conditioned to the use of hypodermic needles that self-injection without a drug may become pleasurable. This phenomenon has raised the question as to whether addicts in treatment should be administered any medication by hypodermic needle for fear of precipitating withdrawal or inducing a craving for heroin. In this study addicts in treatment were given a medicinal needle challenge but there were no documented deleterious effects.

Conditioning, Operant↗

Abnormal adrenal gland metabolism in opioid addicts: implications for clinical treatment.

Adrenal gland metabolism is markedly altered in heroin addicts. During daytime hours, the addict may suffer corticoid deficiency of the addisonian type, and in the evening, an excess of the cushingoid type. The high plasma levels of cortisol that are found in the evening in addicts antagonize endogenous opioids in a manner similar to naloxone. In the present study, 72% of the heroin addicts who sought treatment demonstrated reduced adrenal cortisol reserve. Effective immune and stress responses are dependent on adrenal cortisol reserve. This finding provides an explanation for the heroin addict's vulnerability to AIDS and other infectious diseases. One of methadone's greatest attributes is that it helps normalize adrenal metabolism. Clinical methods to at least partially correct adrenal metabolism may enhance current opioid addiction treatment modalities.

Adrenal Glands↗

Management of traumatic oral-facial injury in the hemophiliac patient with inhibitor: case report.

This report describes identification of Factor VIII inhibitor in a patient who then received immune tolerance therapy. The precipitating event was a traumatic orofacial injury that was nonresponsive to traditional factor-replacement therapies. An inhibitor complicates medical and dental management of the hemophiliac patient because it counteracts usual techniques of hemorrhage control using coagulation agents derived from Factor VIII (Monoclate--Armour, Blue Bell, PA). Successful identification and management of the inhibitor patient require communication and consultation between the physician and dentist, up-to-date knowledge regarding the hemophiliac patient's bleeding and infusion history and aggressive application of local adjunctive hemostatic therapies.

Aminocaproic Acid↗