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F Tomík

Publications and source records attributed to F Tomík.

11 recordsLinked to original sources

[Recurrent polychondritis].

Clinical and histological findings are presented as occurring in a male aged 24 years suffering from relapsing polychondritis (r. p.) of 7 years duration. The presenting symptoms were fever, ataxia, vertigo and vomiting. During the later relapses there also occurred episcleritis, paresis of the glottic muscle and hypertrophic bronchitis. At the age of 22 the patient had had a tracheostomy because of acute respiratory insufficiency. The patient has a typical saddle nose and drooping auricles. Tissues obtained from the auricles showed destructive alterations of the cartilage with fragmentation and homobenization of the elestic fibres. The perichondrium showed fibrosis and a massive round-celled inflammatory infiltration.

Adult

Hemangiopericytoma.

Description of e hemangiopericytomas noted in a 25-(female), 24-(female) and 44-(male) year old patient. Histological examination revealed, besides characteristic appearance of tumor cells, typical arrangement of reticuline. The authors discuss the histological criteria for diagnosis and differential diagnosis and judging benignity and/or malignity of hemangiopericytomas.

Adult

Amyloidosis in rheumatoid arthritis. A study of 48 histologically confirmed cases.

In a group of 269 patients with rheumatoid arthritis histological examination demonstrated amyloidosis in 48 cases, viz. in 7 post mortem cases, in 28 rectal biopsies, in 12 renal biopsies and in one liver biopsy. Examination for amyloidosis was carried out in all patients who had proteinuria, otherwise in non-selected patients with definite rheumatoid arthritis. Even through rectal biopsy is a valuable screening method, it should not be overestimated, because in 12 patients with renal biopsy positive for amyloid, the foregoing rectal biopsies had been negative. According to our experience the most valuable method for diagnosis of amyloidosis in rheumatoid patients is renal biopsy, whereas synovial biopsy is the least conclusive. This paper, according to our knowledge, is the first report on observations of a regression of the inflammatory activity of rheumatoid arthritis and nephrotic syndrome as well as a complete morphological regression of amyloidosis.

Adult