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Biomedical subjects

F Turjman

Publications and source records attributed to F Turjman.

66 records · Page 4Linked to original sources
PubMed1992

Haemorrhagic complications of intracerebral cavernomas: value of MRI.

The authors report a retrospective series of 10 cases of intracerebral haematomas consecutive to cavernomas and studied with MRI. The factors that led to the MRI study were the patients' age and clinical history, the site of the haematoma, the persistence of CT images and a negative arteriography. MRI showed that the haematoma was in contact with the cavernoma in 4 cases and at a distance from it in one case. In 5 cases only the cavernoma was seen at the site of the haematoma. Three patients had multiple cavernomas. In all cases, the diagnosis of cavernoma was confirmed at surgical excision.

Adolescent↗
PubMed1991

Cerebral metastases as first symptom of bronchogenic carcinoma. A prospective study of 37 cases.

Among the patients showing evidence of cerebral metastases without previously known cancer history, lung cancer has been found 37 times as the primary tumor in our institution. There were 34 men and three women and all but two were heavy smokers. Only one presented at diagnosis with thoracic symptoms but the chest radiograph was abnormal in 34. The histologic type of the primary tumor was obtained in 32 cases as a result of thoracic investigations and in five cases from metastatic tumor tissue. The primary tumor appeared to be non-small cell lung carcinoma in 26 cases and small cell lung carcinoma in 11 cases. These results show that patients treated with surgery (20 cases) have a better survival (median 10 months versus 4.5) than the others, and among surgically treated patients only those treated with bifocal resection (eight patients) are long-term survivors. Also, in four of six patients, objective regression of the neurologic symptoms was seen after radiation therapy alone. Central nervous system relapse was seen in 12 patients, but in none of the patients treated with postoperative radiation therapy. Conventional chemotherapy (11 patients) induced objective responses only in the small cell type and proved to be too toxic when used simultaneously with radiation therapy in inoperable patients.

Adult↗
PubMed1991

Magnetic resonance imaging contribution to the diagnosis of spinal cord compression by a subdural arachnoid cyst.

A case of subdural arachnoid cyst of the thoracic spine was studied by magnetic resonance imaging (MRI), myelography and CT myelography. Myelography and especially CT myelography suggested the diagnosis; MRI established it, showing the communication between the cyst and the subarachnoid space. Final characterization was based on surgical findings and pathological examination.

Arachnoid Cysts↗
PubMed1991

[Contribution of imaging in the diagnosis and follow-up of brain tumors].

With the use of modern radiological imaging (US, CT-scan, MRI), the most important informations to recognize a tumor remain the morphological features (localization, size, extension, number of lesions...). The precision of these informations is constantly improved (use of contrast medium, various slices angulations...) and in this field, MRI is the most precise examination. Moreover, these less aggressive investigations allow a repeated and more efficient therapeutic follow-up. In contrast with initial expectations, these radiological investigations do not always allow a formal histological characterization of the different tumor types of the central nervous system, even if some intratumoral components are recognized (fat, calcifications, liquids...).

Brain Neoplasms↗
PubMed1989

[Tumors of the pineal region: MRI aspects. Apropos of 20 cases].

MR imaging (0,5 T) was performed in twenty patients with a tumor of the pineal region (17 pathological correlations). To establish the place of this technique, MR imaging data are studied. There is a great variety of tumor types, but the signal of the tumor is usually non specific. The main indication of MR imaging appears to be the evaluation of the extension of the tumor before surgery.

Adolescent↗
PubMedDate not supplied

Clinical assessment of a new stereoscopic digital angiography system.

PURPOSE: To assess the clinical feasibility of an experimental modified angiographic system capable of real-time digital stereofluoroscopy and stereography in X-ray angiography, using a twin-focus tube and a stereoscopic monitor. METHODS: We report the experience obtained in 37 patients with a well-documented examination. The patients were examined for coronary angiography (11 cases), aortography (7 cases), pulmonary angiography (6 cases), inferior vena cava filter placement (2 cases), and cerebral angiography (11 cases). Six radiologists were asked to use stereoscopic features for fluoroscopy and angiography. A questionnaire was designed to record their subjective evaluation of stereoscopic image quality, ergonomics of the system, and its medical interest. RESULTS: Stereofluoroscopy was successfully used in 25 of 37 cases; diplopia and/or ghost images were reported in 6 cases. It was helpful for aortic catheterization in 10 cases and for selective catheterization in 5 cases. In stereoangiography, depth was easily and accurately perceived in 27 of 37 cases; diplopia and/or ghost images were reported in 4 cases. A certain gain in the three-dimensional evaluation of the anatomy and relation between vessels and lesions was noted. As regards ergonomic considerations, polarized spectacles were not considered cumbersome. Visual fatigue and additional work were variously reported. Stereoshift tuning before X-ray acquisition was not judged to be a limiting factor. CONCLUSION: A twin-focus X-ray tube and a polarized shutter for stereoscopic display allowed effective real-time three-dimensional perception of angiographic images. Our clinical study suggests no clear medical interest for diagnostic examinations, but the field of interventional radiology needs to be investigated.

Adult↗
PubMedDate not supplied

Demonstration of subclavian steal by MR angiography.

We present three cases of subclavian steal syndrome demonstrated by MR angiography. By using a presaturation pulse located at the bottom or at the top of the acquisition volume we demonstrated the flow direction of vertebral arteries. We used a new investigational two-dimensional time-of-flight sequence.

Adult↗
PubMedDate not supplied

Hyperacute diffusion-weighted MRI in basilar occlusion treated with intra-arterial t-PA.

Basilar artery thrombosis should be diagnosed immediately, as intra-arterial thrombolysis might improve the outcome. Diffusion-weighted (DWI)-MRI and three-dimensional time-of-flight MR angiography (3D TOF Turbo MRA) may provide additional insight into the extent of ischemia and the level of the occlusion. These methods could be helpful in the early classification of vertebrobasilar stroke, thus reserving the use of conventional angiography and possible intra-arterial thrombolysis for patients who had a severe clinical picture explained by preliminary assessments. We report the case of a 74-year-old woman who experienced a basilar artery occlusion; DWI-MRI and 3D TOF Turbo MRA provided noninvasive information concerning the level of arterial occlusion and its parenchymal ischemic impact, this leading to an intra-arterial thrombolytic therapy. These data suggest the feasibility of a noninvasive urgent diagnostic and prognostic approach with DWI-MRI and 3D TOF Turbo MRA in basilar occlusion.

Aged↗
PubMedDate not supplied

Diffusion-weighted MRI in acute mutism.

Mutism defined as a complete loss of speech may be related to psychiatric or neurologic disorders. The ischemic stroke origins of mutism are often difficult to assess at the acute stage. Accordingly, the search for the underlying mechanism as the localization of the damages may be difficult by conventional radiological techniques. Diffusion-weighted (DWI) MRI may accurately identify patients with acute ischemic stroke and distinguish them from those who mimic acute stroke better than clinical and conventional neuroradiological methods. This report aims to demonstrate the utility of DWI-MRI in the diagnosis of acute mutism.

Acute Disease↗
PubMedDate not supplied

Endovascular treatment of fusiform aneurysms with stents and coils: technical feasibility in a swine model.

PURPOSE: To assess the biomechanical feasibility of treating experimental fusiform aneurysms endovascularly with a combination of stents and coils. METHODS: An experimental model was surgically constructed in the necks of nine swine to simulate intracranial fusiform aneurysms possessing important "perforators" or side branches. Balloon-expandable metal stents were positioned across the aneurysms in eight swine. In five of these, additional treatment was intraaneurysmal placement of detachable microcoils. Attempts were made to deposit these coils strategically away from the origin of the side branch. RESULTS: Stent placement was successful in seven swine but failed in one swine because of stent-aneurysm size mismatch. Two swine treated with only stents showed no significant alterations in blood filling of the aneurysm or side branch. Satisfactory coil placement (outside the stent, within the aneurysm sac, and away from the orifice of the side branch) was achieved in four of the five swine treated with stents and coils. Careful fluoroscopic monitoring and controlled coil delivery were necessary to avoid covering the sidebranch origin. These aneurysms could not be packed densely after detachment of the first coil because of the resultant radiographic overlap of multiple coil loops on the stent and its lumen in all projections. In one swine there was inadvertent untoward reentry of the coil tip into the expanded stent lumen during its delivery. CONCLUSION: Endovascular treatment of experimental fusiforms aneurysms using stents and coils is technically feasible. The stent maintains patency of the parent artery while allowing strategic coil placement in the aneurysm sac away from the origin of side branches. This technique may prove useful in the future treatment of intracranial fusiform aneurysms. However, potential sources of technical difficulties have been identified, and further longterm studies using an appropriate intracranial stent will be necessary before human application.

Animals↗
PubMedDate not supplied

Inhaled oxygen: a brain MR contrast agent?

Oxygen inhalation led to subtle but readily detectable changes on T2*-weighted images with a conventional MR imager at 1.5 T. We attribute the increase in local signal intensity to changes in blood oxygenation, in particular to a net conversion of deoxyhemoglobin to oxyhemoglobin.

Administration, Inhalation↗