PubMed HealthSearch

Biomedical subjects

F V Dominguez

Publications and source records attributed to F V Dominguez.

At least 19 recordsLinked to original sources

Oral pathology in children. Frequency, distribution and clinical significance.

A statistical study of 1289 biopsies of children 0-15 years old, received at the Pathology Department, Dental Faculty, Buenos Aires University is presented. This number, represents 6.8% of the 18,966 biopsies received from 1960 to 1985. The histologic diagnosis were grouped into the following categories: 1) cysts, 2) tumour-like lesions, 3) inflammatory lesions, 4) neoplasms, 5) neck and head non-oral lesions, 6) dental anomalies and pulp diseases, 7) unclassified diagnosis. Cysts were the most frequent lesion (25.4%). 75% were localized in the jaws and 25% in soft tissue. Bone tumour-like lesions (20.1%) were less frequent than the soft tissue tumour-like lesions (79.9%). Inflammatory lesions and neoplasms in children, account for 15.7% and 10.2% of the lesions respectively. Eighty four percent of the neoplasms were benign and 16% were malignant. Odontogenic tumours constituted 49.6% of all the neoplasms studied. These results indicate the need to be constantly aware of the possible presence of these clinical and radiographic lesions to allow for early diagnosis and adequate treatment.

Adolescent

Silver accumulations in periapical granulomas: report of five cases using the scanning electron microscope, the electron microprobe, and other complementary methods.

A series of cytologic imprints obtained from periapical granulomas were studied with the conventional light microscope, the scanning electron microscope, and the electron microprobe to analyze the chemical composition of several black deposits that were randomly observed near or in the cytoplasm of macrophages and multinucleated giant cells. These granulomas had been removed from endodontically treated human teeth in which the root canals had been obturated with silver cones and Grossman's sealer 3 to 5 years previously. To investigate whether corrosion had occurred on the silver cones, the cones were also examined with the scanning electron microscope and the electron microprobe. Our observations revealed that all the examined silver cones showed different degrees of corrosion on their surfaces, whereas different concentrations of silver, sulfur, and chlorine were detected at the same sites in the cytologic imprints. However, it is impossible to determine from this study whether the presence of corrosive by-products in the periapical tissues is responsible for the development of a pathologic reaction at these sites.

Adolescent

Comparative study of keratocysts, associated and non-associated with nevoid basal cell carcinoma syndrome.

Keratocysts of the solitary type were histologically and histometrically compared with those associated with the nevoid basal cell carcinoma syndrome (NBS). It was observed that parakeratinization, intramural epithelial remnants and satellite cysts were a more frequent finding among NBS keratocysts than among solitary keratocysts. Conversely, it was also found that the total nuclear density was greater in non-associated cysts and that the total number of nuclei, the number of basal nuclei and the epithelial height values were also higher in solitary keratocysts. NBS-keratocysts and solitary keratocysts are considered to be two morphologically distinct populations of the same entity.

Basal Cell Nevus Syndrome

Malignant schwannoma of the gingiva.

A case of malignant schwannoma on the buccal-attached gingiva in the right mandible is described. There was no evidence of multiple neurofibromatosis and the tumor was totally excised. Numerous closely-packed spindle-shaped cells showing marked mitotic activity were seen. The recognizable pattern of neurilemmoma could be observed focally in a small area of the tumor. At two years follow-up, the patient has remained symptom-free with no signs of metastasis.

Adolescent

Ameloblastoma in childhood.

Clinical, radiologic, and histologic studies were performed in eight cases of ameloblastoma in patients younger than 16 years of age. The mean age of the patients was 10.8 years, equal numbers of males and females were affected, and the most common location was the lower molar and ramus areas. Radiologically, a monocystic osteolytic image was observed in all cases. Histologically, two forms of growth were observed: an intramural, infiltrating, plexiform or follicular type, and a polypoid type, prolapsing toward the lumen of a cystic cavity. The ameloblastomas recurred in three cases a year after surgery.

Adolescent

Myxoma of the mandible with unusual radiographic appearance.

Myxoma of the jaws is a fairly frequent bone tumor classified as a benign odontogenic neoplasm. The radiographic picture varies according to its evolution and, it many cases, diagnosis is not easy. A new case with an unusual radiographic appearance is reported. On occlusal radiographic examination the tumor showed multiple spicules of bone with a classic "sun-ray" effect. Only two similar cases were found in the literature. Oral and maxillofacial surgeons should be aware of this unusual presentation so that a misdiagnosis of malignant bone tumor is not made.

Adult

Tissue response to a glass ionomer used as an endodontic cement. A preliminary study in dogs.

A glass ionomer and a standard zinc phosphate were compared with respect to their biocompatibility as endodontic cements. The tissue response was assessed by implantation of both materials in dog tibias. In general, the glass ionomer appeared to provoke a slightly lesser inflammatory response than the zinc phosphate, but this was significant only at the 10- and 30-day observations. At the end of 90 days the tissue response to the tested materials appeared to be similar and the inflammatory picture tended to be resolved with progressive new bone formation. These findings suggest that the tested glass ionomer might adequately replace the zinc phosphate cement as a luting material for endodontic implant stabilizers.

Animals

The formocresol technique in young permanent teeth. A histopathologic study.

Twenty-six extractions were performed at random among seventy-six young, permanent teeth, treated by the formocresol technique, between 5 and 20 months after treatment: twenty-one with penetrating caries (nine vital and twelve nonvital) and five healthy. As a control group, thirteen permanent teeth with penetrating caries were removed: seven vital and six nonvital. The histopathologic analysis compared pretreatment and posttreatment radiographic examinations. In the control cases, there was almost always inflammation and/or necrosis in the entire root canal. In the experimental cases, fibrosis and osteodentin predominated in the apical third, diminishing gradually near the cervical third. Inflammation and necrosis, very low in the apical third, increased similarly near the cervical third. This response seems to be a stage in a process of evolution in biologic scar healing. The complete cure must require a greater lapse of time than that of this experiment--around 10 to 12 months.

Adolescent

Immunocytochemical detection of carcinoembryonic antigen in salivary gland tumors.

The immunoperoxidase method was applied for carcinoembryonic antigen (CEA) detection in biopsy specimens of salivary gland tumors. 9 out of 10 adenoidcystic carcinomas revealed a strong and abundant reaction in tumoral glands. 10 other specimens of pleomorphic adenomas showed weak staining in the areas of epithelial proliferation. Normal glands adjacent to the tumor mass revealed a weak but constant reaction on the luminal border. As in other types of gland tumor, the quantitative estimation of CEA production by salivary gland tumors may be useful in the monitoring of recurrencies.

Adenoma, Pleomorphic

Focal epithelial hyperplasia. Report of five new cases from Argentina.

Five cases of focal epithelial hyperplasia in Argentina from 1968 to 1974 are reported. There was an age range from 11 to 27 years, with an average of 18 years. Three of the patients were born in Jujuy in the northwest corner of the country. Two of these cases were observed in an epidemiologic study carried out among 8,895 20-year-old Argentine men from different areas.

Adolescent