[A clinical study of bonnecor in the treatment of heart rhythm disorders in patients with ischemic heart disease].
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Biomedical subjects
Publications and source records attributed to F V Solov'eva.
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A study was made of the influence of the constant MKM2-1 magnets on patients suffering from essential hypertension. Continuous action of the magnetic field, created by such magnets, on the patients with stage II essential hypertension was noted to result in a decrease of arterial pressure without the occurrence of any side effects and in a simultaneous reduction of the scope of drug administration. Apart from that fact, magnetotherapy was discovered to produce a beneficial effect on the central hemodynamics and microcirculation. The use of the MKM2-1 magnets may be regarded as a feasible method of the treatment of essential hypertension patients at any medical institution.
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Investigation of the hypotensive action of minipress, a drug belonging to the group of selective blockers of alpha 1-adrenoreceptors, shows its efficacy in 56.3 percent of patients with stage II essential hypertension. The side-effects were recorded in 16.6 percent of the patients. It is noted that application of minipress at a mean daily dose of 3.4 ml for a long time reduces the total peripheral vascular resistance without inducing any substantial changes in the stroke volume of the heart or in the pulse rate. At the same time minipress produces a beneficial effect on the microcirculatory blood flow.
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Clinical efficiency of the antiarrhythmic agent palpitin used for the treatment of ventricular and supraventricular extra-systole was assessed in 94 coronary patients, using Holter's ECG monitoring, electrophysiologic studies and rheographic control; reliable evidence in favor of the drug high antiarrhythmic efficiency was obtained.
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Fifty-six patients with acute myocardial infarction aggravated by left ventricular insufficiency were examined. A series of 39 patients received the intravenous instillation of sodium nitroprusside, the remaining 17 patients were given conventional treatment. Hemodynamic parameters and those yielded by precordial mapping at 35 leads were compared over time between the groups. Sodium nitroprusside therapy was related to significant beneficial changes in the hemodynamic parameters and ECG. It is concluded that sodium nitroprusside is highly effective in controlling left ventricular insufficiency in patients with acute myocardial infarction.
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