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Biomedical subjects

F Vít

Publications and source records attributed to F Vít.

At least 19 recordsLinked to original sources

Simple and powerful visual stimulus generator.

We describe a cheap, simple, portable and efficient approach to visual stimulation for neurophysiology which does not need any special hardware equipment. The method based on an animation technique uses the FLI autodesk animator format. This form of the animation is replayed by a special program ('player') providing synchronisation pulses toward recording system via parallel port. The 'player is running on an IBM compatible personal computer under MS-DOS operation system and stimulus is displayed on a VGA computer monitor. Various stimuli created with this technique for visual evoked potentials (VEPs) are presented.

Color↗

Advanced electrophysiological diagnostics of hepatic and portosystemic encephalopathy.

In 28 patients with liver cirrhosis, pre- and post-TIPS (transjugular intrahepatic porta-caval shunt), pattern-reversal visual evoked potentials (PREPs) and motion-onset visual evoked potentials (M-VEPs) examinations, EEG spectral analysis and Number Connection Test were performed. The M-VEPs (representing an activity of the magnocellular system of the visual pathway and reactions of the mediotemporal associate visual area) displayed the highest sensitivity (latencies delay) for detection of subclinical hepatic encephalopathy. The PREPs (originating in the primary visual cortex -area striata) were not significantly changed in comparison with a group of age matched controls. The EEG frequency spectrum exhibited significant slowing of the dominant frequency which was more pronounced in the post-TIPS examination. Combined analysis of the M-VEPs latency and EEG dominant frequency seem to be a recommendable method for early detection and objective classification of subclinical hepatic or portosystemic encephalopathy.

Adolescent↗

Video-signal synchronizes registration of visual evoked responses.

Autodesk Animator software offers the suitable technique for visual stimulation in the registration of visual evoked responses (VERs). However, it is not possible to generate pulses that are synchronous with the animated sequences on any output port of the computer. These pulses are necessary for the synchronization of the computer that makes the registration of the VERs. The principle of the circuit is presented that is able to provide the synchronization of the analyzer with the stimulation computer using Autodesk Animator software.

Computer Graphics↗

Properties of visual evoked potentials to onset of movement on a television screen.

In 80 subjects the dependence of movement-onset visual evoked potentials on some measures of stimulation was examined, and these responses were compared with pattern-reversal visual evoked potentials to verify the effectiveness of pattern movement application for visual evoked potential acquisition. Horizontally moving vertical gratings were generated on a television screen. The typical movement-onset reactions were characterized by one marked negative peak only, with a peak time between 140 and 200 ms. In all subjects the sufficient stimulus duration for acquisition of movement-onset-related visual evoked potentials was 100 ms; in some cases it was only 20 ms. Higher velocity (5.6 degree/s) produced higher amplitudes of movement-onset visual evoked potentials than did the lower velocity (2.8 degrees/s). In 80% of subjects, the more distinct reactions were found in the leads from lateral occipital areas (in 60% from the right hemisphere), with no correlation to handedness of subjects. Unlike pattern-reversal visual evoked potentials, the movement-onset responses tended to be larger to extramacular stimulation (annular target of 5 degrees-9 degrees) than to macular stimulation (circular target of 5 degrees diameter).

Adult↗

[The visual evoked response at the onset of structural movement].

Stimulation by means of moving the structure in the visual field is used to produce visual evoked responses (VER) only rarely. The authors attempted to verify the fact how VER to the movement depended on some stimulation parameters and to compare them with VER to the most frequently used stimulation method, i. e. reversal. Horizontally moving black and white vertical stripes were used with special frequency 2.3 cycles/deg on the screen. It was found that at least 3s interval between two stimuli (between the end of the preceding and onset of the following movements) was necessary and sufficient period of the moving was about 100 ms. Resultant VER are then a reaction on the onset of the movement and are characterized mostly only by marked negative peak with latency being 140 to 200 ms. Opposite to reversal VER, those to the onset of the movement were obtained just in 87.5% of the persons examined (n = 40), in five cases, however, the response to the onset of the motion was higher than that to reversal VER amplitudes were in the latter case highest in the unipolar lead from the right occipital region with the rate of the structure movement being 42 to 84 mm/s.

Evoked Potentials, Visual↗

The use of rotating checkerboard patterns in the treatment of amblyopia.

Sixty-four amblyopic children (mean age 7.5 years, age range 4-12 years) were subjected to treatment using slowly rotating patterns of different spatial frequencies. In 20 amblyopes square-wave gratings (spatial frequencies 0.26-16.84 c/deg), in 44 checkerboard-patterned structures (spatial frequencies 0.04-5.2 c/deg) were used for stimulation. The mean improvement of the distance visual acuity was significantly higher in the checkerboard-stimulated group (3.59 equidistant optotype lines) than in the grating-stimulated group (2.71). As the highest spatial frequency of the checkerboards was substantially lower than of gratings, the results cannot be explained in terms of optical qualities of the stimulating patterns. Other factors, such as short-term occlusion, accomplishment of demanding visuomotor tasks and the quality of cooperation and attentiveness of the patients are considered to be more important for the success of treatment.

Amblyopia↗

Visual evoked responses to pattern-reversal: the signal-to-noise ratio.

Visual evoked responses (VERs) to checkboard-reversal photic stimuli were recorded in 30 healthy experimental subjects with a mean age of 32 years. In 20 cases the stimuli were presented monocularly and in 10 cases binocularly. The estimated mean signal-to-noise ratio (SNR) of the individual VERs was found to be 0.245 +/- 0.092 for monocular stimulation and 0.444 +/- 0.23 for binocular stimulation. The power-based SNR of the averaged VERs was 24.5 and 44.4 respectively. The SNR was raised the most effectively by a new selective averaging variant applied after latency correction of the individual VERs; in the case of monocular stimulation the SNR rose to a mean 58.94 and in binocular stimulation to a mean 87.42. The mean proportion of discarded single VERs was 24%.

Adolescent↗

Pattern-reversal visual evoked potentials in patients with chronic renal insufficiency.

Visual evoked potentials (VEPs) were recorded from 88 patients with chronic renal insufficiency twice at a 6 month interval. In dialysed patients statistically significant decreases in amplitudes and prolongations of VEP peak latencies were found. Azotaemic non-dialysed patients showed related, but smaller, changes in their VEPs. In patients after kidney transplantation the VEP amplitudes were normal but peak latencies were prolonged. No systematic significant relationship between the VEPs and creatinine and urea levels in the blood could be shown.

Brain↗