PubMed HealthSearch

Biomedical subjects

F Vakilzadeh

Publications and source records attributed to F Vakilzadeh.

At least 19 recordsLinked to original sources

[A lupus-vulgaris like atypical mycobacteriosis caused by Mycobacterium xenopi (lupus xenopi)].

A case of lupus-vulgaris-like infection caused by Mycobacterium xenopi in a 62-year-old immunocompetent female patient is presented. A large cutaneous infiltration was seen in the right periorbital region. Histological examination revealed a granulomatous reaction of epithelioid cells and giant cells. M. xenopi was isolated from biopsy material and tuberculosis could be excluded. Isoniazid was effective in healing the lesion within a year. Such infections are well known for other mycobacteria but to our knowledge had not yet been described for M. xenopi. The characteristics of human infections with M. xenopi are summarized in a review of the literature and criteria for the diagnosis of atypical cutaneous mycobacterioses are proposed.

Biopsy

Autosomal dominant ichthyosis exfoliativa.

An unusual ichthyosiform dermatosis with circumscribed areas of blistering hyperkeratoses as well as scaly areas was observed in five consecutive generations of a German family. Light and electron microscopical studies revealed oedema of the keratinocytes in the upper epidermis but no defects of tonofilaments and keratohyalin granules. We suggest that this type of ichthyosis exfoliativa inherited as an autosomal dominant trait represents a new and distinct entity.

Adult

[Bilateral segmental neurofibromatosis].

Segmental neurofibromatosis is a rare type of neurofibromatosis. We report a case of bilateral manifestation, review the literature on this extremely uncommon variant, and discuss the possible causative mechanisms and the genetic risk of segmental neurofibromatosis.

Adolescent

[Erythrokeratodermia anularis migrans--a new genetic dermatosis?].

An unusual type of erythrokeratodermia in an 11-year-old boy is presented. It can be distinguished from the well-known classic types of erythrokeratodermia by clinical criteria, such as the persisting, very slowly migrating, annular lesions, and also by immunohistochemical and ultrastructural findings. In view of the distinct clinical features of this new genodermatosis, the term erythrokeratodermia annularis migrans is proposed.

Biopsy

[Neuropathia mucinosa cutanea].

A 29-year-old man developed progressive, reticular livid skin lesions with neuropathy and hypertrophy of intradermal nerves encased by mucinous material, which has not previously been reported. The name of neuropathia mucinosa cutanea is suggested.

Adult

[Pigmented spindle cell tumor].

The pigmented spindle cell tumor first described by Reed et al. is a benign melanocytic lesion of the skin that frequently remains unrecognized. The tumor is a heavily pigmented macule or plaque that usually appears on the extremities of young patients. The clinical and histological features and the differential diagnosis of pigmented spindle-cell tumor are described with reference to two clinical cases.

Adult

[Pilar sheath acanthoma].

Pilar sheath acanthoma is a rare, benign follicular hamartoma. A case is reported, and the histological and clinical features of this skin tumor are described. The tumor is elevated and characterized by a central punched-out area filled with amorphous whitish material. In contrast to the keratoacanthoma, which has a similar clinical appearance, pilar sheath acanthoma shows no spontaneous regression.

Adult

[Epidermolytic leukoplakia: an unusual precancerous condition].

We report on a rare type of leucoplakia of the lip and the prepuce showing the morphological features of epidermolytic hyperkeratosis. The development of squamous cell carcinoma in one of the patients strongly suggests that epidermolytic leucoplakia may represent a precancerous disorder of the transitional epidermis.

Aged

Relapsing linear acantholytic dermatosis.

A 5-year-old girl with a unilateral linear systematized skin lesion showing the clinical, histological and ultrastructural features of Hailey-Hailey disease is described. We suggest that this relapsing linear acantholytic dermatosis represents a new distinct entity within the spectrum of unilateral linear skin diseases.

Acantholysis

[Pomade crust].

Exaggerated use of skin care topicals in infants may lead to brownish appositions in the inguinal and gluteal region described as pomade crust. Examination of scraping material by infra-red spectroscopy failed to reveal any residue of emollients but instead was characteristic of human scales. Certain topicals are apparently capable of inducing hyperkeratosis in these body regions.

Age Factors

[Acne vulgaris].

Explore the source record for details and available documents.

Acne Vulgaris

[Clinical findings in porphyria cutanea tarda].

Disturbances in the iron metabolism can quite frequently be observed in patients with porphyria cutanea tarda. Studies on 10 patients with porphyria cutanea tarda indicate that elevated iron levels are correlated with decreased latent and normal total iron binding capacity in the serum. Morphological examinations of the liver showed alterations as can be found in fatty liver up to cirrhosis, which -- in most instances -- were associated with iron deposits in the hepatocytes.

Adult

[Linear pigmentation of nails].

A case of linear pigmentation of three fingernails is reported. Following extraction of the nail of the thumb the matrix displayed a 2X4 mm circumscribed pigmented area. Histologic examination revealed a junction nevus.

Adult

[Ascher's syndrome].

A case of Ascher's syndrome with blepharochalasis and double upper lip is described. It is emphasized that the combined appearance of these two symptoms is essential for the definition of this syndrome.

Blepharoptosis