PubMed Health⌕ Search

Biomedical subjects

F Veselý

Publications and source records attributed to F Veselý.

6 recordsLinked to original sources
PubMed1992

[Malignant cystosarcoma phyllodes].

The authors deal with the clinical and pathological aspects and histopathological criteria of malignity of cystosarcoma which are important from the aspect of assessment of the extent and type of surgical intervention. Large malignant cystosarcomas and cystosarcomas taking up the whole breast with damage of the skin are indicated for simple mastectomy, while small malignant cystosarcomas (i. e. in relation to the size of the breast) can be treated by a wide local excision with a safety margin, as some primary as well as recurrent phylloid tumours behave in a benign way or may transform into a fibroadenoma or a dysplastic focus. Moreover contrary to carcinoma of the breast, there is no association with a multicentric character of the disease. Axillary lymph nodes are only rarely affected; therefore dissection of the nodes is not necessary.

Adult↗
PubMed1992

[Cystosarcoma phylloides in adolescent women].

The authors describe four cases of juvenile fibroadenoma (benign form of cystosarcoma phyllodes) in pubertal girls aged 11-15 years. They reflect on the variable behaviour of this rare tumour and differentiate the relations between fibroadenoma, virginal hypertrophy of the breast, juvenile fibroadenoma, giant fibroadenoma and cystosarcoma phyllodes. A dominant position is held by surgical treatment which is strictly individualized. The authors recommend, similarly as many other authors, an extensive excision of the tumour with a safety margin and in case of repeated relapses or the very rare malignant form which frequently behaves as a benign tumour. The operation is made in the submammary groove or on the lateral margin of the breast which ensures an excellent cosmetic effect. The authors do not consider excision of superfluous skin or reconstruction of the breast necessary with regard to the elastic properties of the skin and the capacity of the mammary gland to develop.

Adolescent↗
PubMed1989

[Immunomodulation therapy of breast carcinoma with levamisole].

The authors present results of modality and immunomodulating treatment of breast cancer. In the treatment they use levamizole (Decaris) which has useful properties, as compared with other immunomodulating drugs--accurate dosage, simple administration and good tolerance. In a group of 84 patients it was administered after operation after adjuvant chemotherapy with Cyclophosphamide in a total dose of 300 mg orally, making check-up examinations of leucocytes and thrombocytes. As to other laboratory parameters, the authors assessed transaminases, alkaline phosphate, immunoglobulin, T-lymphocytes and carcinoembryonic antigen. During the same period the survival of patients in this group was significantly higher, as compared with a group of patients formerly treated by adjuvant chemotherapy with Cyclophosphamide without levamizole. Comparison of the results with those of other authors indicates that it is correct to include immunomodulating treatment in comprehensive treatment of breast cancer.

Adjuvants, Immunologic↗