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Biomedical subjects

F Vin

Publications and source records attributed to F Vin.

33 records · Page 2Linked to original sources

[Inflammation and subcutaneous calcification of venous origins].

There have been few descriptions up to now of calcifications in chronic venous insufficiency, other than in cases where venous insufficiency is complicated be severe trophic disorders and in particular ulcers. It was therefore felt to be of interest to assess the presence of calcifications in venous insufficiency without trophic disorders. This study was based upon 40 cases recruited in the phlebology out-patient clinic of the Notre Dame de Bon Secours Hospital. Calcifications of the lower limbs were found in 7 patients, either by palpation, routine X-rays or ultrasonography. The etiopathogenic mechanisms of this occurrence not having been elucidated, a number of hypotheses are put forward on the basis of acquired data concerning: the process of formation of ectopic calcifications, changes in subcutaneous tissue, the ultimate consequences of venous stasis and of raised venous pressure, due essentially to anoxia and inflammation. One hypothesis can thus be put forward: that of inflammation. The release of cells and mediators of inflammation, the production of free radicals, causing damage to the cells of connective tissue and to the organic framework (collagen fibres) and changes in the chemical environment could combine to result in the formation of calcifications in subcutaneous tissue. However, inflammation has not been proven to be the primary etiological factor.

Adult↗

[Comparative study of the effectiveness of continuous or intermittent courses of a phlebotonic drug on venous disorders disclosed or aggravated by oral, estrogen-progesterone contraceptives].

In patients with venous disorders related to oral contraceptives, venotonic treatment should be prescribed for as long as contraception is maintained. 2,295 patients between the ages of 20 and 40 years with venous insufficiency revealed or aggravated by oral contraceptives were randomised to receive venotonic treatment for one month either continuously or in parallel with active contraceptive treatment, from the 10th to the 28th day. The results demonstrated the values of prolonged treatment of venous disease, as its effects persisted and were reinforced with time. The possibility of intermittent prescription would appear to improve compliance and lower the cost of treatment while ensuring comparable long-term efficacy.

Adult↗

[Echo-sclerotherapy of the external saphenous vein].

Echo-sclerotherapy involves the injection of a sclerosing agent into an incompetent varicose vein under ultrasonographic control. This method can be used in the treatment of all varicose veins of the legs but is of particular value when clinical examination is insufficient or difficult because of the large number of anatomical varieties encountered or when the patient is obese and sclerosing injections alone then become difficult. It is chiefly indicated at neurovascular junction sites since injections are much safer because of twin visual control of the syringe and in situ on the ultrasonographic screen. Used during injections of the sapheno-popliteal junction, a region considered to be dangerous, it should enable avoidance of extremely serious complications of sclerosing injections and more particularly that of intra-arterial injection.

Humans↗

[Clinical semeiology of the perforating veins in essential varicosis in the postphlebitic syndrome].

After a reminder of the anatomy of the perforating veins of the lower extremities and their physiopathology, various clinical aspects are presented. In the essential form of varicose veins disease, long saphenous refluxes are, at the beginning, responsible for stasis in the superficial venous system. During the course of the disease, it seems that the perforators become incontinent. In the post-phlebitic syndrome, the manifestations are different and there are numerous perforators, the topography of which depends on the location of the thrombosis. A well conducted clinical examination is absolutely necessary in order to demonstrate the origin of the long or short reflux, before the start of any treatment. In case of failure or recurrence, phlebography or varicography must be performed.

Humans↗

[Improper local corticotherapy in phlebology. Apropos of a case].

Referring to a case history, we remind you that local corticotherapy can have considerable cutaneous side-effects. We describe the case of a patient treated for more than five years for periulcerous eczema by combined triamcinolone and neomycine. This treatment was responsible for cutaneous atrophy and the detachment triggered off a phenomenon which we compare to the corticoidal dermatitis observed following the detachment of prolonged local corticotherapy on the face. The discussion is brought to bear on the method of detachment, which can be either harsh or gentle, using corticoids which are milder, or without fluorine, in the degressive process.

Administration, Topical↗

[Report of an update on products used in the treatment of ulcers].

We have studied some of the new products either at experiment stage, or else already on the market, used in the treatment of leg-ulcers. In terms of the way in which they act we draw a distinction between: synthetic powders with adsorbent power (Bard and Iodosorb); synthetic dressings with a semi-adsorbent power (Aloxan and Silastic); and synthetic dressings with no adsorbent power (Synthaderm). We give a personal impression of each of them, together with their indications, advantages, and disadvantages.

Humans↗

[Clinical study of the postphlebitic syndrome].

The syndrome is approached from the diagnostic and developmental point of view. The clinical examination remains of paramount importance, for it is necessary to differentiate between the primary varices and the post-phlebitic varices which have the same functional symptoms. The main trophic complications are listed, principally: oedema, hypodermititis, ochrodermititis and leg ulceration, which is the most formidable complication and which still occurs very frequently. Ulceration is likely to occur more frequently following sural phlebites rather than those higher up. The main topographical areas of varices are described, without forgetting the collateral circulation in the abdominal and subpudendal region. The developmental aspect of post-phlebitic syndrome is difficult to predict as sequels appear after varying lengths of time, and in varying ways. Finally, venous functional investigations have a practical advantage. They make it possible to assess the functional state of the limb by indicating precisely the state of the deep and superficial circulation. They can thus make it possible to assess the importance of venous stasis and the nutritional state of the tissues.

Humans↗

[Varices of the lower limbs and pregnancy].

Pregnancy, a causal factor and very often a revealing element of varicose veins, is still viewed by many as an obstacle to their treatment. The inclusion of its role in the development of the varicose vein should be based on different theories--dynamic, histochemical and biochemical--which, far from being in confrontation are complementary and which the authors attempt to summarize. Clinical treatment of pregnancy varices does not differ from that of ordinary venous deficiency varices, but the speed with which the varices appear and the speed of their development necessitates an effective treatment. The best treatment of pregnancy varices is still their prevention, essentially by sclerosis, resort to surgery being advisable only after the last pregnancy. Venotropes and elastic support should preferably be used during pregnancy if necessary. Sclerotherapy, which is remarkably effective, will only be reserved for the cure of a painful or ulcerous problem, or if there is risk of varicose rupture.

Clothing↗