Resonance neutron capture in 136Ba.
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Biomedical subjects
Publications and source records attributed to F Voss.
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The objective was to assess the usefulness of serum progesterone concentrations in the differentiation of intra-uterine (viable and non-viable) and extra-uterine pregnancies. Progesterone concentrations were prospectively measured at 4, 5 and 6 weeks gestation in 338 pregnancies which resulted in 242 viable births, 81 abortions and 15 ectopic pregnancies. Progesterone threshold analysis was performed using receiver-operator characteristic curves. The progesterone threshold value for ectopic pregnancy at 4 weeks was 5 ng/ml, at 5 weeks 10 ng/ml and at 6 weeks 20 ng/ml. A significant difference was observed between all intra-uterine versus ectopic pregnancies (P = 0.0005), but not between viable versus non-viable intra-uterine pregnancies (P = 0.37). The differences were most clearly defined at 4 weeks and decreased with increasing gestation. We conclude that serum progesterone and gestational age taken together can differentiate intra-uterine from extra-uterine pregnancies with a very high sensitivity and specificity at 4 weeks gestation, a time when ectopic pregnancies are not evident on ultrasound examination.
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Urinary tract infections in girls are promoted by abnormal micturition habit. Aside from applying antibiotics, the training of voiding discipline is very important for UTI prevention. The duration of medicamentous prevention should pay regard to the behaviour of micturition.
First affection with urinary tract infection, relapses, and micturition pattern were analyzed depending on age. It is demonstrated that the decreased UTI rate after the 12th year rather depends on the micturition habit than on puberty.
The normalization of functional micturition disturbances obtains an increasing importance in the treatment and guidance of girls with urinary tract infections. Our experience in the detection of an abnormal micturition pattern is reported. A detailed interrogation of the parents feasible in any outpatient practice is more emphasized than investigations by means of technical devices.
Aside from antimicrobiotic therapy, the training of micturition discipline is an inalienable part in preventing urinary tract infections. The delay of voiding until imperative desire to urinate must be avoided. The child has to learn to urinate immediately when desire is urgent, but further to urinate prospectively before new plays are begun. Experiences with this training program are reported.
About 400 girls with non-obstructive urinary tract infection were submitted to special care for at least one year, mostly considerably longer, however. Being searched for functional micturition disturbances, more than one-half of them showed a habit of delaying the micturition until imperative desire to urinate. Girls with this habit had clearly more relapses of UTI than those voiding regularly.
Relapse rate of urinary tract infection in girls with functional micturition disturbances by far exceeds that under normal micturition habits. When the habit of micturition can be normalized or at least considerably improved the relapse rate is distinctly lowered, a causal nexus thus can not be doubted.
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