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Biomedical subjects

F W Flickinger

Publications and source records attributed to F W Flickinger.

14 recordsLinked to original sources
PubMed1990

Intraorbital tumor as the initial symptom of childhood acute lymphoblastic leukemia. Magnetic resonance imaging findings.

Orbital involvement in leukemia is usually of myelogenous origin and is frequently the initial presentation. Orbital tumor due to lymphocytic leukemia is rare and only one case has been reported as the initial symptom. We report magnetic resonance imaging (MRI) findings of a case of acute lymphocytic leukemia with orbital mass as the initial symptom. The usefulness of MRI, including signal intensity and extent of involvement, is discussed.

Child, Preschool↗
PubMed1990

I-131 accumulation in gastric pull-up simulating pulmonary metastases on total-body scan for thyroid cancer.

A follow-up total-body I-131 scan in a patient with follicular thyroid carcinoma demonstrated radionuclide accumulation in the right hemithorax. Originally thought to be pulmonary metastatic thyroid carcinoma, the uptake region proved to be intrathoracic gastric mucosa. The patient had been treated for squamous cell esophageal carcinoma by esophagogastrostomy reconstruction with gastric pull-up. This unusual imaging pattern could have been interpreted as metastatic disease in the absence of complete patient records, an appreciation of normal gastric concentration patterns of I-131, and corroborative imaging study analysis.

Carcinoma, Squamous Cell↗
PubMed1990

Indium-111-leukocyte/technetium-99m-MDP bone and magnetic resonance imaging: difficulty of diagnosing osteomyelitis in patients with neuropathic osteoarthropathy.

Fourteen patients (16 sites) with clinical and/or radiographic evidence of neuropathic osteoarthropathy (Charcot joints) were evaluated with combined indium-111-leukocyte (111In-WBC) and technetium-99m-methylene diphosphonate (99mTc-MDP) bone imaging for suspected osteomyelitis. Magnetic resonance (MR) images were obtained in seven patients. Using a positive bone culture as the criterion for the presence of osteomyelitis, there were four true-positive studies, six true-negative sites, and one false-negative 111In-WBC study. Five of 16 sites (31%) had false-positive 111In-WBC uptake at noninfected sites. There were four true-positive and three false-positive MR studies. All false-positives showed at least moderately abnormal findings by both techniques at sites of rapidly progressing osteoarthropathy of recent onset. In this preliminary study, both techniques appear to be sensitive for detection of osteomyelitis, and a negative study makes osteomyelitis unlikely. However, the findings of 111In-WBC/99mTc-MDP and MR images at sites of rapidly progressing, noninfected neuropathic osteoarthropathy may be indistinguishable from those of osteomyelitis.

Adult↗
PubMed1978

Radionuclide scan findings in delayed splenic rupture.

An initial liver/spleen scan performed on a patient with blunt abdominal trauma was negative 3 days following the accident. A follow-up scan 7 days later showed definite evidence of splenic rupture, proved surgically. The authors conclude that, in such cases, spleen scans may be negative initially because of delayed splenic ruptures.

Abdominal Injuries↗
PubMedDate not supplied

MRI in hyperparathyroidism requiring reoperation.

A 34-year-old woman presented with persistent hyperparathyroidism (HPT) following primary surgical removal of a hypertrophied parathyroid gland. Reevaluation ultrasound (US), computed tomography (CT), and parathyroid scintigraphy studies were negative for parathyroid adenoma. Magnetic resonance imaging (MRI) clearly identified an ectopic parathyroid adenoma within the lateral carotid sheath. Uncomplicated surgical extirpation of the adenoma was accomplished. We discuss the role of US, CT, parathyroid scintigraphy, and MRI in recurrent HPT.

Adenoma↗
PubMedDate not supplied

Lumbar epidural chordoma: MR findings.

Chordomas derive from persistent nests of notochordal cells that do not regress. They usually arise from the midline within bone of the skull base or spinal column. Typical radiographic findings of chordomas include midline location and bony destruction. We report an unusual epidural chordoma of the lumbar spine.

Adolescent↗
PubMedDate not supplied

Neurilemoma of the tongue: MR findings.

Neural tissue tumors of the oral cavity are rare. They are found most commonly in the tongue and arise from the sheaths of peripheral nerves, neuroglia, and neurons. We report magnetic resonance findings in a case of neurilemoma of the tongue.

Adult↗