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Biomedical subjects

F W Hehrlein

Publications and source records attributed to F W Hehrlein.

At least 109 records · Page 6Linked to original sources

Coronary and contractile reserve in the dog heart with chronic multiple coronary occlusions before and after aortocoronary bypass.

Peak isovolumetric left ventricular pressure and dp/dtmax before and after norepinephrine (N.E.) infusion and cross-clamping of the aorta was identical in normal dogs and in dogs with chronic coronary artery occlusion (C.C.O.) before and after aortocoronary bypass. In normal dogs, coronary reserve was 7.9 and 7.4 times control for the subendocardium and the subepicardium. After C.C.O., coronary reserve was 7.0 and 5.7 times control in the normal area and 2.4 and 3.5 times control in the collateral dependent area (endo vs. epi). After N.E. myocardial blood flow increased to 57% of the coronary reserve in normal dogs, and to 100% in dogs with C.C.O. After bypass, myocardial blood flow normalized. In dogs with C.C.O., N.E. stimulated the contractile reserve maximally and the coronary reserve is completely expended.

Animals↗

[Acupuncture analgesia for open heart surgery (author's transl)].

The first clinical results of 100 patients, operated since November 1973 using ECC and acupuncture anesthesia are reported. The method of combined chinese and european procedures of analgesia is described. Advantages and problems of the new method are discussed.

Acupuncture Therapy↗

[Early experiences with arterial heterografts (author's transl)].

Since April 1975 we used 50 bovine arterial heterografts for reconstructive surgery after chronic arterial occlusions or for the production of AV-shunts needed for chronic dialysis. In none of the cases incompatibility was seen. The early results (with a follow-up period of 6-10 months) after femoro-popliteal bypass were excellent, as far as a good peripheral run off was present. Several shunts (n = 7) containing 2-3 transplants, are still functioning 3-10 months after implantation. At present, we use bovine transplants in reconstructive vessel surgery when a thrombendarterectomy or the connection of venous grafts is impossible or when the operative procedure should be kept short in high-risk patients. To produce AV-shunts in patients with renal insufficiency we prefer this type of grafts when all conventional techniques were already used.

Animals↗

[Early and late complications due to direct and indirect aortic-isthmus-Plastic (author's transl)].

During the last 20 years 156 patients underwent a direct and indirect aortic-isthmus-plastic. Early complications occurred in 7.6%. 5 patients developed an aneurysm in the area of isthmus-plastic. The mortality rare was 4.5%. There was no evidence of recurrent coarctation in a group of children and in adult patients. The indirect aortic-isthmus-plastic first described by Vosschulte represents an elegant surgical method of functionally reestablishing the aortic lumen by retaining the posterior wall for further growth potential. This technique can be performed with a low mortality rate and no recurrent coarctation of the aorta.

Adolescent↗

[Combined acupuncture analgesia and controlled respiration. A new modified method of anesthesia in open heart surgery (author's transl)].

From October 1973 to May 1975 cardiae surgery with extracorporal circulation using Acupuncture as Analgesia was performed in 131 patients in the surgical clinic of the University of Giessen. Acupuncture is performed by electric-stimulation of 8 points at the lower legs, the neck and ears with 90 V and 5--6 Htz. All patients are intubated; controlled respiration is maintained with 50% O2 and 50% N2o. During the whole operation, 20 min after intubation the patients are responsible. The main advantage of the new method we see in a good postoperative cooperation of the patients, which are generally extubated in the operation-room.

Acupuncture Therapy↗

[Acupuncture analgesia and controlled respiration. A new modified method of anesthesia in open heart surgery (author's transl)].

From October 1973 to February 1975 cardiac surgery with extracorporal circulation using Acupuncture as analgesia was performed in 88 patients in the surgical clinic of the University of Giessen. Acupuncture is performed by electric-stimulation of 8 points at the lower legs, the neck and ears with 90 V and 5-6 Hz. All patients are intubated; controlled respiration is maintained with 50% O2 and 50% N2O. During the whole operation, 20 minutes after intubation the patients are responsible. The main advantage of the new method we see in a good postoperative cooperation of the patients, which are generally extubabed in the operation room.

Acupuncture Therapy↗

[Immunologic aspects to the prevention of infection cardiac surgery (author's transl)].

1. The humoral immunosystem is impaired in those cases of catabolic metabolism in which quantitative and qualitative insufficient alimentation is expected after operation. 2. We showed that after cardiac surgery with extracorporal circulation as well as after other operations a reasonably balanced parenteral nutrition composed of carbohydrates and amino acids could considerably inhibit the changes in the humoral immunity, which is a valuable contribution to the prevention of infection. 3. In our experiments on transformation of lymphocytes after mitogenic stimulation, the depressive effects of operation on the cellular immunity were found to be etiologically more complex than was previously assumed in publications.

Bronchoscopy↗

[Aortic valve replacement for acute heart failure due to infective endocarditis (author's transl)].

5 patients with primary infective endocarditis developed acute cardiac failure because of aortic valve insufficiency. 2 patients were in the active and 3 patients in the inactive stage of infective endocarditis. In 4 patients an aortic and in 1 patient an aortic and mitral valve replacement was performed. The early mortality rate (death within 30 days of operation) was 20 per cent. Once congestive heart failure starts during the course of active endocarditis surgery should be undertaken at an early date.

Acute Disease↗