PubMed Health⌕ Search

Biomedical subjects

F Warwick

Publications and source records attributed to F Warwick.

5 recordsLinked to original sources
PubMed1985

Sclerosing-cholangitis-like changes in pancreatic disease.

In a retrospective analysis of endoscopic cholangiograms in 66 patients with pancreatic disease we found sclerosing-cholangitis-like changes in 83% of cases. Excluding patients with intrapancreatic constriction of the distal common bile duct, 70% of patients with chronic pancreatitis, 60% with acute pancreatitis and 100% with pancreatic cancer had these abnormalities. The possible significance of these changes, which are unlikely to be secondary to pancreatic disease, are discussed with reference to the published literature on sclerosing cholangitis.

Adult↗
PubMed1982

Relationship between pancreatic exocrine function and ductal morphology in chronic pancreatitis.

Forty-five patients with chronic pancreatitis (of whom only 14 had pancreatic calculi) were investigated by endoscopic pancreatography and the secretin-pancreozymin test in order to explore the relationship between exocrine function and duct morphology in this disease. Each pancreatogram was assigned a score that ranged from 1 when the duct system was normal to 6 when a chain-of-lakes replaced the main duct; the scores attained were compared with the respective secretory volumes, bicarbonate concentrations, bicarbonate outputs, and trypsin outputs of exocrine secretions. Although a significant negative correlation emerged in each instance, the secretory overlap between the six subgroups was so marked as to render impractical any prospect of accurately predicting the pancreatogram appearance on the basis of prevailing pancreatic function in any individual case, or vice versa. The likely explanation for this result is that (a) chronic pancreatitis is a patchy process in which the acini and ducts are variably affected, and (b) destruction of parenchyma and obstruction to drainage of secretions contribute in varying proportions to the decrease in exocrine function.

Bicarbonates↗
PubMedDate not supplied

Factors associated with a perceived harmful outcome from medication errors: a pilot study.

The purpose of this pilot study was: 1) to describe factors associated with a perceived harmful outcome following medication errors made by nurses and 2) to refine the Medication Error Risk Profile (MERP) (Wolf, 1992). Ninety-four registered nurses and licensed practical nurses completed the MERP. Multiple stepwise regression analyses were used to explain the variance in the dependent variable of perceived patient harm with: 1) phases of preparation and administration; 2) categories of person responsible for the error; 3) interventions needed following the error and symptoms related to the error. The exploratory regression analysis suggests a model in which the dispensing phase of administration, the physician and pharmacist categories of persons responsible for the error, and the interventions of patient transfer to another unit and additional medications given following the error explain 53% of the variance in perceived harmful outcome for patients consequent to medication errors. A moderately strong correlation (r = .46, P < .001) existed between perceived patient harm as measured on the four-point scale and total intervention score following medication errors.

Adult↗