[Fluspirilene--safe weekly tranquilizer?].
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Adult↗
Biomedical subjects
F Welter
Publications and source records attributed to F Welter.
[Cranial magnetic resonance tomography--value in diagnosis of dementia. Important additional information for differential diagnosis].
The clinical data and the magnetic resonance imaging (MRI) findings of 41 patients with clinically diagnosed dementia of the Alzheimer type (DAT) and 20 age-matched healthy controls were evaluated with the aim of determining the value of MRI in the diagnosis and differential diagnosis of dementia. Patients and controls with cerebrovascular risk factors, including a history of stroke, were excluded from the analysis. The MRI findings of patients with dementia revealed pathological changes, in particular cerebral atrophy (p < 0.0005), significantly more frequently than did those of controls (p < 0.005). Periventricular demyelinisation and lesions of the white matter were found in 23 (56%) patients, and in 6 (30%) of the controls. MRI revealed one case each of subdural hematoma, hydrocephalus and cerebral amyloid angiopathy. In 14 patients, the detection MRI scans of cerebral infarctions or hematomas suggested a major vascular component of the dementia. In contrast, lesions of the white matter can not reliably by ascribed to a vascular etiology. On the basis of our findings, it is concluded that cranial MRI is of great value for the differential diagnosis of dementia, even when the clinical diagnosis of Alzheimer's dementia is probable and cerebrovascular risk factors are absent.
Aged↗
[Cerebrovascular diseases in advanced and very old age. Significance and correlation of computer tomography studies of the skull and EEG].
118 patients between 50 and 90 years of age with an acute cerebrovascular disease were examined. While cranial computerized tomography was helpful in the differential diagnosis of ischemia or hemorrhage it was less helpful in the diagnosis of other cerebrovascular diseases (abnormalities, stenoses). Frequent EEG-analysis permitted in the cases of cerebral ischemia or hemorrhage prognostic conclusions as well as computerized tomography did. Atypical clinical syndromes could be better diagnosed by computerized tomography than by EEG.
Age Factors↗
[Socio-medical aspects in aged patients with pacemaker (author's transl)].
After a medical examination in the pacemaker ambulance 37 patients were questioned of their personal problems in connection with the implantation of a pacemaker. The level of information, their attitude towards the pacemaker-system, and their anxieties. From the results the clue was drawn that in medical treatment patients should be adequately informed when the indication of a pacemaker is told. A comparative analysis of information leaflets supplied by pacemaker producers and the results of the interviews with the patients show that those leaflets influence the level of information of the patient less than expected. There are significant differences in the patients' compliance. The majority of the patients (84%) don't check their own pulses regularly. On the other hand the survey shows excellent results in compliance of patients taking medicine. An analysis of postoperative changes in attitude and behavior shows a great number of patients which still retain their previous role even their state of health improved significantly after the implantation. On the other hand some patients reported improvements but their records indicated a decompensation (placebo effect).
Adaptation, Psychological↗
[Long-term findings regarding blood pressure in geriatric patients with pacemaker (author's transl)].
The chronic behavior of blood pressure of 151 ventricle were examined in a study which was set up in a prospective way. The implanted pacemakers were fit out with ventricle controlled Demand-Systems. The period of the observation lasted between 25 and 62 month. After the implantation a decrease of the systolic pressure value is to expect. Precautions to overcome this phase must be taken. The blood pressure from the greater part of the patients increased after three or five month to the values, which were taken before the implantation. The medicinal therapy has to consider for this change of the behavior of blood pressure. Only a little number of pacemaker patients (n = 10) showed during the long-term course a durable decrease of the systolic blood pressure.
Adult↗
[The cardiovascular system and cerebrovascular disorders in the elderly with special reference to pacemaker therapy].
Elderly patients are problem patients, especially as far as the selection of the best therapy is concerned. The reduction of cerebral efficiency is caused by a reduced metabolism and blood circulation of the brain. Extracerebral disturbing factors comprise obstructions of the vascular system, disturbances of the pumping action of the heart, changes of blood pressure and a lack of substrates. The symptoms are of a great variety, they may occur in a slowly progressive or an acute form. The pacemaker treatment shows the close connection between diseases of heart and circulation and the cerebral vascular circulation. This treatment improves the contraction of the heart, but it also causes an improvement of the cerebral vascular situation, especially in patients with chronical bradycardiac arrhythmias, demonstrated by a series of EEG investigations and clinical controls. New methods of "physiological" heart stimulations are important in patients having cerebralsclerotic disturbances, whereby the collaboration between cardiologists and neurologists should be intensified.
Aged↗