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F Willekens

Publications and source records attributed to F Willekens.

8 recordsLinked to original sources
PubMed2002

A cardiovascular life history. A life course analysis of the original Framingham Heart Study cohort.

AIMS The objective of this paper is to measure the potential burden of cardiovascular disease within the original Framingham Heart Study cohort by transforming its well-described epidemiological measures into time-based health policy measures, such as life years lost to or lived with the disease. METHODS AND RESULTS We constructed multi-state life tables of the Framingham Heart Study cohort to calculate dwelling times with a history of cardiovascular disease. Age-specific probabilities determined transitions from healthy through disease to death. For this synthetic cohort, from age 50 men (women) live on average 26 (32) years; 20 (26) free of cardiovascular disease. Allowing occupancy of more than one disease state, 50-year-old males (females) live 2 X 9 (1 X 2) years with a history of myocardial infarction, 0 X 93 (1 X 2) with a history of stroke, and 0 X 67 (0 X 93) with congestive heart failure. Having ever suffered acute myocardial infarction, stroke or congestive heart failure, life expectancy is reduced by 9 (13), 12 (15) or 16 (16) years, respectively in 60-year-old men (women). CONCLUSIONS Transforming occurrence probabilities into time-based health measures, the prevalence of cardiovascular disease is remarkable: from age 50, 20% of remaining life expectancy is lived with the disease. Such measures are integral to appropriate health planning and assessment of the potential population health value of various treatment and prevention strategies.

Adult↗
PubMed1994

Monitoring international migration flows in Europe. Towards a statistical data base combining data from different sources.

"The paper reviews techniques developed in demography, geography and statistics that are useful for bridging the gap between available data on international migration flows and the information required for policy making and research. The basic idea of the paper is as follows: to establish a coherent and consistent data base that contains sufficiently detailed, up-to-date and accurate information, data from several sources should be combined.... The issues may be tackled more easily if the statistics that are being compiled are viewed as different outcomes or manifestations of underlying stochastic processes governing migration. The link between the processes and their outcomes is described by models, the parameters of which must be estimated from the available data.... The paper discusses the experience of the U.S. Bureau of the Census in combining migration data from several sources. It also summarizes the many efforts in Europe to establish a coherent and consistent data base on international migration." (SUMMARY IN FRE)

Americas↗
PubMed1992

Analysis of mortality data from the former USSR: age-period-cohort analysis.

The objective of this article is to review research on age-period-cohort (APC) analysis of mortality and to trace the effects of contemporary and historical factors on mortality change in the former USSR. Several events in USSR history have exerted a lasting influence on its people. These influences may be captured by an APC model in which the period effects measure the impact of contemporary factors and the cohort effects the past history of individuals which cannot be attributed to age or stage in the life cycle. APC models are extensively applied in the study of mortality. This article presents the statistical theory of the APC models and shows that they belong to the family of generalized linear models. The parameters of the APC model may therefore be estimated by any package of loglinear analysis that allows for hybrid loglinear models.

Adolescent↗
PubMed1983

Migration and settlement: a multiregional comparative study.

"In 1976, the International Institute for Applied Systems Analysis initiated a study of migration and population distribution patterns in its seventeen member nations. In each country, the analysis was carried out by national scholars using techniques of multiregional demography. In this paper the authors describe the organization of the study, discuss the data bases used, evaluate the main results obtained, and review some of the methodological research that has been generated by the study. Among the...conclusions are recommendations for researchers wishing to carry out a multiregional demographic analysis." Consideration is given to national and subnational patterns of mortality, fertility, and migration; age composition; and regional population distribution.

Age Distribution↗
PubMedDate not supplied

Trends and sex-differentials in Dutch mortality since 1850: insights from a cohort--and period--perspective.

"This paper makes use of a recently established comparative series of period and cohort life tables for the Netherlands for the period 1850-1991. Trends in period and cohort life expectancy at birth for males and females are discussed. A simple spline function is used to identify turning points in these trends. Trends in the contribution of specific age groups to the changes in life expectancy and to male excess mortality were studied using the Arriaga method. For this purpose, the results of period and cohort analysis were compared." (SUMMARY IN ITA AND FRE)

Age Factors↗