[Polyarthritis in anisakiasis. 1st case].
Explore the source record for details and available documents.
Acute Disease↗
Biomedical subjects
F X Fabresse
Publications and source records attributed to F X Fabresse.
[Role of dapsone in the treatment of Horton's disease and polymyalgia rheumatica].
The authors report 8 cases of Horton's disease and/or polymyalgia rheumatica treated with prednisone with an initially favourable result. However, the disease progressed despite relatively high dose steroid therapy, complications of which contraindicated increasing the dosage and even necessitated rapid withdrawal of steroids. The association of dapsone 100 mg/day orally had a rapid favourable effect in all 8 cases. However this treatment was well tolerated in only 3 patients and could only be continued in 4 out of the 8 cases. Manifestations of intolerance (methemoglobinaemia) rapidly regressed after withdrawal of dapsone but this was followed by another exacerbation of the disease, resulting in a therapeutic impasse. Despite the incidence of these iatrogenic complications, dapsone would appear to provide a therapeutic option in patients with Horton's disease and/or polymyalgia rheumatica resistant to high dose steroid therapy or in whom complications of steroid therapy impose a reduction in dosage or complete withdrawal of the drug.
Aged↗
[Bone localisation of Hodgkin's disease. A report on 13 cases (author's transl)].
The authors review 13 cases of bone localisation of Hodgkin's disease taken from 120 case-reports, and compare the findings with those reported in the published literature. The frequency of bone lesions in this series was 18%. Initial signs were clinical in one half of the cases and radiological or scintigraphic in the other half. Early diagnosis of bone lesions was more frequently made in this series than late discovery of bone locations; the lesions ware more frequently present in the spine, the pelvis, and the sternum; the usual appearance was osteolytic or mixed, lytic and condensed. Scintigraphy is a reliable early diagnostic procedure, as is medullary biopsy which has become essential for the investigation of extension of the lesions. An inflammatory syndrome is present in most cases. In this series, bone lesions usually were of haematogenic origin and were mainly of the scleronodular histological type. Definite recovery was obtained in more than half of the cases. In the other patients, the bone lesions coincided with a long disease course, were never the reason for great concern, and were never directly responsible for death in the 3 patients that died.
Adolescent↗