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F Zamfirescu

Publications and source records attributed to F Zamfirescu.

9 recordsLinked to original sources

[Towards a day care hospital. V. Does repetition of the Newman test induce learning?].

Newman's test consist in draw a line on two parts of a figure made of points. This test was achieved in four successive trials by thirteen boys and fourteen girls, all voluntary students. In two trials subjects wear Reiser screen which reduce to a slight extent distinctness of vision. Trial order was randomised. For each trial, time performance and four numeral criterions of graphic defects were compared to initial values. The test retest values are no significantly different. Reiser screen alter some criterions. So the Newman test is useful to assess awakening on condition that such criterion were used in reference to subject preanaesthetic values and with controlled conditions of environment.

Adolescent

[Active or postural prisms].

Oculomotor visual input of the postural system can be modified with a small powerful prism from 1 to 4 dioptries. The determination of features acting on postural tonus through visual and oculomotor input is difficult. It is necessary to examine postural and oculomotor consequences of each optical correction.

Eyeglasses

[Orthoptics].

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Adult

The effect of somatostatin analogue on chiasmal dysfunction from pituitary macroadenomas.

The long-acting somatostatin analogue SMS 201-995 has been shown to be efficient in the treatment of somatotropic and thyrotropic adenomas. In some cases, it can suppress adenoma secretion and lead to tumor shrinkage. Pituitary macroadenomas are often associated with a vision-threatening chiasmal syndrome. In this series, SMS 201-995 was administered subcutaneously to eight patients with pituitary macroadenomas of various types responsible for severe long-lasting visual defects. An obvious improvement of both visual fields and acuity occurred in six patients, in two of these during the first 4 to 6 hours of treatment; in two patients, gonadotropic adenomas were unresponsive. Maximal improvement (normalization of visual fields in three cases) occurred within 6 to 45 days and was sustained during the 1- to 12-month follow-up period. This effect seems independent of the type of adenoma since the adenomas secreting growth hormone (GH) and thyroid-stimulating hormone and silent corticotropic-secreting adenomas responded as well as did two of the non-functioning adenomas. In one acromegalic patient visual improvement was obtained while the abnormal GH secretion remained unaltered. In all cases but one, no tumor shrinkage could be demonstrated. These data demonstrate that SMS 201-995 can rapidly improve the chiasmal syndrome due to pituitary macroadenoma, and suggest that this effect might be independent of a reduction in tumor volume.

Adenoma

[A protocol for monitoring antimalarial treatment].

We are showing a protocol to survey the treatment by APS, with a computer equipment that enable us to examine very shortly the central field of vision and the ERG; but that least investigation can be EOG or a PEV, according to the toxic pathology we are studying.

Antimalarials