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Biomedical subjects

F de Oliveira

Publications and source records attributed to F de Oliveira.

18 recordsLinked to original sources

Halo structure of (14)Be.

The two-neutron halo nucleus (14)Be has been investigated in a kinematically complete measurement of the fragments ((12)Be and neutrons) produced in dissociation at 35 MeV/nucleon on C and Pb targets. Two-neutron removal cross sections, neutron angular distributions, and invariant mass spectra were measured, and the contributions from electromagnetic dissociation (EMD) were deduced. Comparison with three-body model calculations suggests that the halo wave function contains a large nu(2s(1/2))(2) admixture. The EMD invariant mass spectrum exhibited enhanced strength near threshold consistent with a nonresonant soft-dipole excitation.

Journal Article↗

[Left ventricular aneurysm. The surgical results and follow-up].

From May 1988 through October 1994, 44 patients with ischemic left ventricular aneurysm were operated upon. The mean age was 60.5 +/- 7.7 years and 36 patients (81.8%) were male. Thirty-two patients (72.7%) had congestive heart failure in NYHA class II or greater and 26 (59.1%) had moderate or severe left ventricular dysfunction. In 41 cases (93.2%) there was a history or electrocardiographic signs of myocardial infarction and only 3 patients (6.8%) were angina free. The location of the aneurysms was antero-apical or antero-lateral in 37 patients (84.1%) and inferior in 7 (15.9%), and intracavitary clot was present in 9 cases (20.5%). Fifteen patients (34.1%) were operated upon using standard linear repair, 8 (18.2%) by Stoney's technique and in the remaining 21 (47.7%) an endoventricular patch plasty was performed. All patients but one had CABG with a mean of 2.7 grafts per patient. The IMA was used in all patients with graftable LA disease (90.0%). Double IMA grafting was used in 10 patients (22.7%). Three patients (6.8%) had associated valvular surgery. Hospital mortality was 2.3% (1 patient) and morbidity 22.7% (10 patients); intra-aortic balloon counterpulsation was required in two patients. The mean time of hospitalization was 13.5 +/- 9.0 days. In the follow-up period (mean 29.2 +/- 21.5 months), 6 patients had required hospitalization (left ventricular failure -4; supraventricular arrhythmia-2) and two died. The remaining 32 survivors (78.0%) are in functional class I of the NYHA, without angina. Surgery of left ventricular ischaemic aneurysm was possible with low mortality and morbidity, with good functional results.

Adult↗

[Surgery for acute type-A aortic dissection].

From January 1989 through June 1996, 29 patients underwent surgical repair of type A acute aortic dissection. Mean age was 59 +/- 13.5 years (range 25-76 yrs) and 21 patients (72.4%) were male. Nineteen patients (65.5%) had systemic hypertension and 3 (10.3%) Marfan syndrome. One patient (3.4%) had prior surgical repair of descending aortic dissection and CABG. Six patients (20.7%) were operated on in shock. The dissection was limited to the ascending aorta (DeBakey type II) in 12 patients (41.4%). Eleven patients (37.9%) had severe aortic regurgitation. Replacement of the ascending aorta was performed in all cases and extended to include the transverse arch in one. Twenty-three patients (79.3%) were operated upon using a tubular graft (sacron-21, homograft-2) with aortic valve resuspension. In the remaining 6 (20.7%) the aortic valve and root were replaced using a Bentall procedure, modified with a homograft in 3 cases. Five patients (17.2%) had associated surgery: CABG (4) and closure of aortic-atrial fistula (1). Mean cardiopulmonary bypass time was 134 minutes (range 70 to 285 min) and aortic cross-clamp time was 58 minutes (range 23 to 93 min). Hypothermic circulatory arrest for open distal anastomosis was used in 26 patients (89.7%) (mean time 22 min; range 10 to 32 min), with retrograde cerebral perfusion in the last 4 years (18 cases; 62.1%). Hospital mortality was 17.2% (5 patients). Eight patients (27.6%) had hospital morbidity: reexploration for bleeding (4 cases), CVA (3), A-V block necessitating permanent pacemaker (1). The mean time of hospitalization was 18 days (range 9 to 81 days). In the follow-up period (mean 38 mths; range 4 to 94 mths), 2 patients died (CVA and gastrointestinal bleeding) and 4 required hospitalization (perforated duodenal ulcer, peritonitis, suspected endocarditis, supraventricular tachyarrhythmia-1 patient each). All 22 survivors (75.9%) returned to the functional status they had prior to the dissection and 18 of them (81.8%) are in NYHA functional class I. Type A acute aortic dissection is a complex pathology and the postoperative mortality remains significant, but surgery permits good functional recovery and an active life for the survivors.

Acute Disease↗

Congenital posterolateral diaphragmatic hernia in the adult.

Bochdalek's hernia, congenital posterolateral diaphragmatic hernia, is common in children but rarely occurs in adults. The authors report two such adult cases. One of the hernias was on the left and the other on the right. Both patients had gastrointestinal symptoms. The approach was abdominal in one and thoracoabdominal in the other. There were no operative or postoperative complications. The possibility of congenital posterolateral diaphragmatic hernia must be considered in the differential diagnosis of patients who have recurrent gastrointestinal and respiratory complaints. A complete roentgenologic examination is necessary in order to make an accurate diagnosis preoperatively. Because of the danger of strangulation of the hernia, operation should be carried out as soon as the diagnosis is made.

Adult↗

Malignant leiomyoblastoma (epithelioid leiomyosarcoma) of the duodenum.

Leiomyoblastoma of the stomach is exceedingly rare. The authors report the case of a 69-year-old woman who presented with acute epigastric pain, anemia and weight loss. She was found to have a malignant leiomyoblastoma (epithelioid leiomyosarcoma) of the duodenum with lymph-node involvement. The clinical and pathological aspects of leiomyoblastoma of the gastrointestinal tract are reviewed, with emphasis on the distinctive, diagnostic histologic features. To the authors' knowledge, this is only the fourth reported case of leiomyoblastoma of the duodenum and the only case in which the tumour was malignant.

Aged↗

Traumatic diaphragmatic hernias: a report of 19 cases.

From an analysis of 19 patients with traumatic diaphragmatic hernias with respect to the type of injury, associated injuries, clinical and radiologic features, diagnosis, surgical management and causes of death and from a review of the literature, the authors draw a number of conclusions. 1. Careful clinical examination coupled with an accurate interpretation of the roentgenograms should detect most cases of traumatic rupture of the diaphragm. 2. Impairment of respiratory function, possibility of strangulation and incarceration of the abdominal viscera demand early repair. 3. The choice of incision and approach depends on the stage at which the rupture is recognized (early or late), the site of rupture and the associated injuries. 4. Careful assessment of respiratory function should be made in order to prevent postoperative complications; in some cases respiration must be assisted. 5. Although the mortality in patients with traumatic diaphragmatic rupture is still relatively high, the deaths sould not be related to the rupture per se, or to its repair, but rather to the associated injuries.

Adolescent↗