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Biomedical subjects

F del Castillo

Publications and source records attributed to F del Castillo.

5 recordsLinked to original sources

[Infectious mononucleosis in children].

50 cases of infectious mononucleosis by Epstein-Barr virus were studied in patients over and under 4 years age. Clinical evolution did not show any statistical differences between both age groups, except for splenomegalia which was more common in children under 4. Serology was divided into 3 groups: children under 4 year, between 4 and 5 and those over 5 years of age. First group exhibited a positive Davinsonh test in 15.3% of cases; second group in 33.3% and third in 80%. IgG antibodies against virus capsid were positive in 86% of cases with an equal distribution according to age groups. IgM antibodies were positive in 66%, not exhibiting any disparity in age groups.

Adolescent

Some comments on the variance of heterozygosity in finite populations.

A new and more accurate formula for the variance of heterozygosity under genetic drift has been obtained. The variance can be partitioned into two components; the first comes from the dispersion of the allelic frequencies among populations, and the second from the dispersion of the actual heterozygosity, h, around their expected values, 2pq. A certain generation exists where the variance reaches a maximum; thus, the genetic drift can be split into two phases by this single maximum.

Biological Evolution

[Abdominal tuberculosis in children. A review apropos of 13 cases].

Thirteen cases of abdominal tuberculosis are presented; some of them in active or symptomatic stage and others in latent or abdominal calcification form. Many of these patients were diagnosed through the finding of a source of infected cattle after diagnosis of one of symptomatic patients. Pathogenesis, clinical findings and diagnostic difficulty are commented, as well a sanitary importance of the problem, since M. bovis is still a currently found organism in daily practice.

Adolescent