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Biomedical subjects

F el Baba

Publications and source records attributed to F el Baba.

11 recordsLinked to original sources

Choroidal melanoma with pigment dispersion in vitreous and melanomalytic glaucoma.

A 39-year-old black man underwent enucleation of the left eye because of poor vision, ocular pain, and intractable glaucoma secondary to a choroidal tumor. Two diagnostic vitrectomies, performed 11 and 7 months before enucleation, had failed to disclose the proper diagnosis. Histologic diagnosis was necrotic malignant melanoma of the choroid with melanocytoma cells, extensive pigment dispersion throughout the eye, and melanomalytic glaucoma. Possible mechanisms of tumor necrosis are reviewed.

Adult

Nonsimultaneous primary choroidal and cutaneous melanomas. Report of a case.

The authors report a patient with nonsimultaneous choroidal and cutaneous melanomas. The patient did not display the dysplastic nevus syndrome phenotype, and there was a negative family history for cutaneous or uveal melanomas. This sporadic case might suggest a common etiologic factor in the pathogenesis of multicentric malignant melanomas.

Choroid Neoplasms

Uveal neovascularization at the ora serrata and pars plana.

Thirty-two eyes with uveal neovascularization at the ora serrata and pars plana were studied histopathologically. Chronic retinal detachment of various etiologies was the most frequently associated feature, present in 65% of the patients. In three eyes, the neovascularization took the form of an angiomatous lesion, whereas in the others, capillaries, arterioles, and venules were present. A history of glaucoma was found in 60% of the patients. Other associated findings included choroidal rupture, vitreous hemorrhage, and a history of cryotherapy. Uveal neovascularization at the ora serrata should be considered in the differential diagnosis of retinal angiomas, retinal telangiectasia, malignant melanoma, adult Coats's disease, peripheral proliferative retinopathies, and vitreous hemorrhage.

Adult

Abnormal ocular head postures: Part III.

All patients exhibiting the various types of abnormal head postures of ocular origin that were seen during the last two years are presented in order to determine the relative frequency of the different causes of these postures, and the purposes they serve. The treatment modality and results are also discussed. The manuscript is divided into four parts: Parts I, II, and III concern head postures in incomitant strabismus. In Part IV, head postures in Ciancia's syndrome, restrictions, and refractive errors are described.

Fixation, Ocular

Abnormal ocular head postures: Part IV.

All patients exhibiting the various types of abnormal head postures of ocular origin that were seen during the last two years are presented in order to determine the relative frequency of the different causes of these postures, and the purposes they serve. The treatment modality and results are also discussed. This manuscript is divided into four parts: Parts I, II, and III concern head postures in incomitant strabismus. In Part IV, head postures in Ciancia's syndrome, restrictions, and refractive errors are described.

Adolescent

Abnormal ocular head postures: Part I.

All patients exhibiting the various types of abnormal head postures of ocular origin that were seen during the last two years are presented in order to determine the relative frequency of the different causes of these postures, and the purposes they serve. The treatment modality and results are also discussed. The manuscript is divided into four parts: Part I, II, and III concern head postures in incomitant strabismus. In Part IV, head postures in Ciancia's syndrome, restrictions, and refractive errors are described.

Child

Abnormal ocular head postures: Part II.

All patients exhibiting the various types of abnormal head postures of ocular origin that were seen during the last two years are presented in order to determine the relative frequency of the different causes of these postures, and the purposes they serve. The treatment modality and results are also discussed. The manuscript is divided into four parts: Parts I, II, and III concern head postures in incomitant strabismus. In Part IV, head postures in Ciancia's syndrome, restrictions, and refractive errors are described.

Duane Retraction Syndrome

Clinicopathologic correlation of lipidization and detachment of the retinal pigment epithelium.

A 49-year-old woman had a few small drusen-like lesions and one larger area of depigmentation in the right fundus. The pin-point lesions corresponded to single enlarged retinal pigment epithelial cells with lipid accumulation and the larger area represented a small, localized retinal pigment epithelial detachment (soft druse). Lipoidal degeneration of individual retinal pigment epithelial cells may be a mechanism of nodular drusen formation. The soft druse was associated with thickening of the basement membrane of the retinal pigment epithelium.

Female

Malignant melanoma at the site of penetrating ocular trauma.

We document clinically and histopathologically the development of a uveal melanocytic tumor at the site of penetrating ocular trauma in a 34-year-old man. A metallic intraocular foreign body was extracted via the inferonasal pars plana with an electromagnet in February 1975. At that time no intraocular tumor was noted and the visual acuity returned to 20/20. The patient developed floaters in January 1981, at which time findings from fundus examination and needle biopsy of the lesion suggested the presence of a spindle-cell melanoma. The diagnosis was confirmed histopathologically following enucleation. The possible association between trauma and ocular melanoma is discussed.

Adult

Massive hemorrhage complicating age-related macular degeneration. Clinicopathologic correlation and role of anticoagulants.

Reported are 15 cases of age-related macular degeneration (AMD) complicated by massive subretinal and/or vitreous hemorrhage. Clinicopathologic correlation is presented in four of the seven cases studied histopathologically. Salient histologic findings include: subretinal and subretinal pigment epithelium (sub-RPE) fibrovascular scar in the posterior pole; discontinuities in Bruch's membrane with choroidal neovascularization; extensive hemorrhagic detachment of the RPE and sensory retina; and vitreous hemorrhage. In three cases, a choroidal artery, emerging from breaks in Bruch's membrane, had ruptured walls. The authors have reviewed the previously reported cases of AMD complicated by massive hemorrhage and found that 19% of the patients were taking Coumadin (warfarin) or aspirin treatment when the bleeding occurred. Forty percent had a positive history of systemic hypertension and cardiovascular diseases. Although the occurrence of hypertension is expected in the aged population with AMD, use of anticoagulants or antithrombotics by such patients may predispose them to serious ocular hemorrhagic complications.

Aged

Melanocytoma of the ciliary body: presentation of four cases and review of nineteen reports.

A clinical and histopathologic review of 23 cases of melanocytoma of the ciliary body discloses that the tumor is unilateral, extends into contiguous structures, slowly enlarges, and commonly undergoes necrosis. We report the clinical and histopathologic features of four cases of melanocytoma of the ciliary body, review the previously reported and presented cases, and discuss the differential diagnosis of melanocytoma of the ciliary body.

Adult