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Biomedical subjects

Farhan Taghizadeh

Publications and source records attributed to Farhan Taghizadeh.

4 recordsLinked to original sources

Mandibular setback by sagittal split ramus osteotomy: a 12-year follow-up.

Short- and long-term skeletal changes after mandibular setback were analyzed using bilateral sagittal split ramus osteotomy. Twelve patients who had undergone mandibular setback surgery between 1986 and 1990 were available for long-term cephalography on average 12 years after primary surgery. The mean amount of surgical setback had been 6.4 mm. After the first postoperative year, there was skeletal relapse of 1 mm at the B-point and pogonion (Pg), amounting to 14% of the initial skeletal setback. In contrast to condylar displacement and proximal segment rotation, osteotomy slippage was associated with positional changes at the B-point and Pg. From 1 to 12 years postoperatively, the B-point and Pg remained stable. Mandibular ramus and corpus length decreased 2.1 mm and 1.3 mm, respectively, indicating remodeling at the osteotomy sites and probably condylar resorption.

Adolescent↗

Pharmacological treatments for rhinosinusitis.

Acute bacterial rhinosinusitis (ABRS) is a well-recognised and common problem confronting many primary care physicians but the abuse of antibiotic therapy for viral aetiologies of ABRS has lead to widespread bacterial resistance. The once easily-eradicated pathogens have developed many mechanisms to resist antimicrobial therapies. The most common pathogens Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis are still found in cultures of sinus cavities but Staphylococcus and possibly some anaerobes play an important role in the development of the chronic stage of rhinosinusitis. The choice of antibiotic therapy for both ABRS and chronic rhinosinusitis (CRS) are reviewed, along with considerations for ancillary therapy. Note is made of the role of chemical mediators in the inflammatory stage possible strategies to reduce this problem. Allergic fungal rhinosinusitis results from a hypersensitivity reaction to demetiaceous fungi. Cure of the effects of rhinosinusitis depends on the establishment of a healthy sinus cycle.

Anti-Bacterial Agents↗

Evaluation of hydroxyapatite cement for frontal sinus obliteration after mucocele resection.

OBJECTIVES: To retrospectively evaluate our experience with frontal sinus obliteration using hydroxyapatite cement (BoneSource; Stryker Biotech Europe, Montreux, Switzerland) and compare it with fat obliteration over the approximate same period. Frontal sinus obliteration with hydroxyapatite cement represents a new technique for obliteration of the frontal sinus after mucocele resection. METHODS: Exploration of the frontal sinus was performed using bicoronal, osteoplastic flaps, with mucosal removal and duct obliteration with tissue glue and muscle or fascia. Flaps were elevated over the periorbita, and Silastic sheeting was used to protect the BoneSource material from exposure as it dried. The frontal table was replaced when appropriate. RESULTS: Sixteen patients underwent frontal sinus obliteration with fat (fat obliteration group), and 38 patients underwent obliteration with BoneSource (BoneSource group). Fat obliteration failed in 2 patients, who underwent subsequent BoneSource obliteration, and none of the patients in the BoneSource group has required removal of material because of recurrent complications. Frontobasal trauma (26 patients [68%] in the BoneSource group and 9 patients [56%] in the fat obliteration group) was the most common history of mucocele formation in both groups. Major complications in the BoneSource group included 1 patient with skin fistula, which was managed conservatively, and 1 patient with recurrent ethmoiditis, which was managed surgically. Both complications were not directly attributed to the use of BoneSource. Contour deficit of the frontal bone occurred in 1 patient in the fat obliteration group and in none in the BoneSource group. Two patients in the fat obliteration group had donor site complications (hematoma and infection). Thirteen patients in the BoneSource group had at least 1 prior attempt at mucocele drainage, and no statistical relation existed between recurrent surgery and preservation of the anterior table. CONCLUSION: Hydroxyapatite is a safe, effective material to obliterate frontal sinuses infected with mucoceles, with minimal morbidity and excellent postoperative contour.

Adipose Tissue↗