Biomedical subjects

Fazl Q Parray

Publications and source records attributed to Fazl Q Parray.

3 recordsLinked to original sources

PubMed2006

Nontraumatic terminal ileal perforation.

BACKGROUND: There is still confusion and controversy over the diagnosis and optimal surgical treatment of non traumatic terminal ileal perforation-a cause of obscure peritonitis. METHODS: This study was a prospective study aimed at evaluating the clinical profile, etiology and optimal surgical management of patients with nontraumatic terminal ileal perforation. RESULTS: There were 79 cases of nontraumatic terminal ileal perforation; the causes for perforation were enteric fever(62%), nonspecific inflammation(26%), obstruction(6%), tuberculosis(4%) and radiation enteritis (1%). Simple closure of the perforation (49%) and end to side ileotransverse anastomosis(42%) were the mainstay of the surgical management. CONCLUSION: Terminal ileal perforation should be suspected in all cases of peritonitis especially in developing countries and surgical treatment should be optimized taking various accounts like etiology, delay in surgery and operative findings into consideration to reduce the incidence of deadly complications like fecal fistula.

Journal Article↗

PubMedDate not supplied

Primary lymphoma of the spleen: an experience with seven patients.

Primary lymphoma of the spleen is a rare clinical entity. In our study, a group of 110 patients with various hematological disorders were subjected to splenectomy over a period of 20 years. We have been able to isolate 7 patients with primary lymphoma of the spleen. Main indications of splenectomy in these patients were anemia and leukopenia. There was no mortality, but morbidity was quite high (43%). We conclude that splenectomy may be a useful treatment in patients with cytopenias secondary to primary lymphoma of the spleen refractory to other types of therapy.

Adult↗

PubMedDate not supplied

Splenectomy in idiopathic hypersplenism.

The therapeutic effects of splenectomy in 15 patients with idiopathic hypersplenism were studied. The mean age was 43 years (range, 5-72 years). The male to female ratio was 1:1.14. The response to splenectomy was: in thrombocytopenia, complete response (CR) in 71%, partial response (PR) and no response (NR) in 14% each of patients; in anemia, CR in 83%, PR in 0%, and NR in 16% of patients; and in leukopenia, CR in 78% and PR and NR in 11% each of patients. However, the morbidity (27%) and mortality (20%) observed was quite high. Thus, we conclude that splenectomy is an excellent treatment to improve the hematological parameters in patients with idiopathic hypersplenism, but elderly patients and patients with multisystem disease should not have this surgery.

Adolescent↗