Biomedical subjects

Fenfang Li

Publications and source records attributed to Fenfang Li.

4 recordsLinked to original sources

PubMed2006

Mechanism of the enhanced degradation of pentachlorophenol by ultrasound in the presence of elemental iron.

Ultrasound combined with elemental iron (US/Fe(0)) is effective in oxidizing organic contaminants in water. The sonolysis degradation of pentachlorophenol (PCP) was significantly enhanced by a factor of 4.2 with the addition of elemental iron, mainly via reaction with hydroxyl radicals (OH radicals), and the synergistic mechanism of the enhancement in the combined system was investigated. Experiments were performed with (1) sole ultrasonic treatment; (2) ultrasound in presence of iron; (3) ultrasound combined with copper powder as the same particle size as iron powder; (4) ultrasound in presence of Fe(II). It was observed that PCP degradation and OH radicals production were both enhanced in these combined methods, and the pitting on the sonicated iron surface was apparent. These results indicated that the rate enhancements in US/Fe(0) system were attributed to (1) the iron solid effect and the catalysis of Fe(II) produced from corroded-iron with promoting the production of OH radicals; (2) the increased surface area of iron particles by acoustic cavitation with promoting the adsorption process.

Catalysis↗

PubMed2005

Methicillin-resistant Staphylococcus aureus, Hawaii, 2000-2002.

The emergence of methicillin-resistant Staphylococcus aureus (MRSA) has generated considerable concern among medical and public health professionals. We used a statewide, population-based antimicrobial resistance surveillance system to examine epidemiologic trends for MRSA from outpatients and inpatients in Hawaii. Pediatric and adult patient populations were compared to assess characteristics of MRSA isolates specific for each group. From 2000 to 2002, 8,206 (26%) of 31,482 total S. aureus isolates were MRSA. During this period, the proportion of MRSA isolates increased in both outpatient and inpatient clinical settings (p<0.01). When stratified by age, annual trends showed a significant increase in the proportion of MRSA in adult patients (from 24% to 30%, p<0.01) but not in pediatric patients (from 25% to 27%, p>0.05). Although MRSA isolates from adults demonstrated high resistance to most non-beta-lactams, most MRSA isolates from pediatric outpatients remained susceptible to most non-beta-lactams.

Adolescent↗

PubMed2005

Isolate removal methods and methicillin-resistant Staphylococcus aureus surveillance.

The effect of duplicate isolate removal strategies on Staphylococcal aureus susceptibility to oxacillin was compared by using antimicrobial test results for 14,595 isolates from statewide surveillance in Hawaii in 2002. No removal was compared to most resistant and most susceptible methods at 365 days and to the National Committee for Clinical Laboratory Standards (NCCLS) and Cerner algorithms at 3-, 10-, 30-, 90-, and 365-day analysis periods. Overall, no removal produced the lowest estimates of susceptibility. Estimates with either NCCLS or Cerner differed by <2% when the analysis period was the same; with either method, the difference observed between a 90- and a 365-day period was <1%. The effect of duplicate isolate removal was greater for inpatient than outpatient settings. Considering the ease of implementation and comparability of results, we recommend using the first isolate of a given species per patient to calculate susceptibility frequencies for S. aureus to oxacillin.

Anti-Bacterial Agents↗

PubMed2002

[Therapeutic regimen in Vogt-Koyanagi-Harada syndrome].

OBJECTIVE: To compare the effectiveness of therapeutic regimen in Vogt-Koyanagi-Harada (VKH) syndrome and determine the reasonable regimen for different patients. METHODS: Data of 82 patients with VKH syndrome, coming from all over China and referred to Zhongshan Ophthalmic Center from January 1996 to December 2000 were retrospectively analyzed. Twenty-eight patients (56 eyes) with first attack of the intraocular inflammation were treated with oral prednisone for more than one year, whereas 54 patients (108 eyes) with recurrent episodes were treated with chlorambucil for more than one year. All patients were treated with a combination of these immunosuppressives with traditional Chinese medicine herbs, and followed up more than one year after systemic treatment. The previous treatment for these 54 patients was also analyzed in an attempt to compare these results with those presented here. RESULTS: Uveitis was completely controlled in 96.4% of the patients treated with oral prednisone, and all of these patients showed improved vision after treatment. A complete control of uveitis was achieved in 94.4% and improved vision was seen in 88.0% of the patients treated with chlorambucil. All of these 54 patients, although treated with longer but intermittent systemic corticosteroids before installation of chlorambucil, showed a chronic or recurrent uveitis and most cases had markedly decreased vision as compared with those treated by us with regular systemic corticosteroids. CONCLUSIONS: Intensive and prolonged systemic treatment with corticosteroids is recommended for the patients with first attack of VKH syndrome, where as regular treatment with chlorambucil is useful for control of chronic and recurrent uveitis seen in VKH syndrome. Traditional Chinese medicine herbs may be helpful in amelioration of uveitis and reduction of side effects of immunosuppressives.

Adolescent↗