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Biomedical subjects

Florentina Pricop

Publications and source records attributed to Florentina Pricop.

6 recordsLinked to original sources

Diagnostic hysteroscopy in endometrial hyperplasia.

OBJECTIVES: To assess the reproducibility of hysteroscopic diagnosis in the various types of endometrial hyperplasias and to compare different classifications of endometrial hyperplasia from this point of view. STUDY DESIGN: 109 endometrial hyperplasias, diagnosed in the last 5 years with hysteroscopy, were all biopsied and had a pathological examination. We tried to estimate the accuracy of hysteroscopy comparing the various classifications of endometrial hyperplasia to the final pathologic diagnosis. RESULTS: Using older endometrial hyperplasia classification, the overall diagnostic accuracy of hysteroscopy was 76% as for the correct type of hyperplasia. Classifying them at hysteroscopy into two categories only, i.e. hyperplasias and neoplasias, gave a more accurate result (90.26%). CONCLUSIONS: The newer classification is better from the hysteroscopist's point of view.

Diagnosis, Differential↗

[Dicephalic conjoined twins-a case report].

Presentation of a case of dicephalic conjoined twins, rare malformation with an incidence of 1:50000. Before dissection, the specimen was investigated by CT, x-ray and ultrasound. Dissection was performed under Zeiss surgical microscope and the images were taken with a Sony video line. Specimens for histologic examination were collected. The parents refused genetic examination. The complex study of the specimen allowed us to make the following diagnosis: dicephalus dibrahii dipus conjoined twins. In the past 20 years no such case was reported in Romania. An etiological diagnosis is impossible. Embryologically, we support the fusion theory (Winslow) promoted by O'Rahily (1998): gemellarity disturbance during the first week of pregnancy.

Abnormalities, Multiple↗

[Pelvic-perineal prolapse of 3rd grade after subtotal hysterectomy].

The pelvi-perineal prolapse (PPP), which is a relatively well defined anatomo-clinical and surgical entity, involves a complex etiology and pathogeny. The relatively rapid appearance of PPP after subtotal hysterectomy without the suspension of the vaginal stump and perineal reconstruction has already been substantiated. This study refers to a similar case, where it was necessary to apply some non-typical surgical technics (cervical stump extirpation, colpoligamentopexy with 4 non-resorbable threads at the Cooper ligaments and perineal reconstruction), with the aim of vaginal suspension, at a menopausal patient with PPP of 3rd degree, stress urinary incontinence, ulcerating remaining cervix and cystorectocele, installed at 2 years after the inter-annexal subtotal hysterectomy.

Female↗

[Ultrasonographic assessment of fetal pathology in the first trimester of pregnancy].

The fetal pathology can be diagnosed even from the first trimester of pregnancy using ultrasonographic markers. We tried to follow only one of them, that is nuchal translucency. We measured it in 166 low risk pregnancies after the established protocol. We used both the technique of sequential screening (to establish the chromosomal risk) and the likelihood ratio of the nuchal translucency for the cardiac (nonchromosomal) pathology. We found a rate of 3.61% cases with high risk for fetal disorders. In these ones is better to use diagnostic investigations such as genetic or morphologic assessment during the second trimester.

Adolescent↗

[Cerebro-umbilical ratio--high fidelity indicator in ante-partum fetal disorder].

In this study, we have aimed to point out the reliability and importance of the cerebro-umbilical ratio obtained by Doppler exploration, in comparison with classical investigations, as well as to verify the diagnosis of ante-partum foetal disorder through the amount of the Apgar score at the fetuses having been monitored.

Apgar Score↗

[Diagnostic difficulties in mammary gland adenosis. Case report].

Tumor adenosis represents a rare lesion, which most frequent appears as a palpable mass, with more than the usual dimensions. The paper presents a case of tumor adenosis of the mammary gland of a 16 years girl. Macroscopically, the tumor was well delimited, with gray-white surface and a nodular aspect on section. The tissue was processed by routine technique and stained with hematoxylin-eosine (H&E). There were also performed immunohistochemical (Actin SM, CK, S100) and special stainings (silver impregnation). Microscopically, there were observed several histologic types of adenosis, the most frequent being sclerosing adenosis. Through silver impregnation it was observed that the basement membrane, which surrounded the tubes, was intact. Immunohistochemically, there were evidentiated the epithelial and myoepithelial components of the tubes. The presence of these elements led through the diagnosis of tumor adenosis. The importance of recognition of the tumor adenosis is found in the possibility of wrong interpretation of this with tubular invasive carcinoma, these two entities being often mistaken, mainly at the frozen-section examination.

Adenocarcinoma↗