Biomedical subjects

Florian Wiesinger

Publications and source records attributed to Florian Wiesinger.

5 recordsLinked to original sources

PubMed2006

Coil setup optimization for 2D-SENSE whole-heart coronary imaging.

Accelerated "whole-heart" coronary imaging with sensitivity encoding applied in both phase encoding directions (2D-SENSE) was investigated. In order to maximize the signal-to-noise ratio (SNR), coil configuration optimization was performed. To this end, 10 practical coil configurations each consisting of six standard coil elements were investigated and the local SNR was assessed by means of phantom experiments. Based on the experimental data, a symmetric configuration was found to yield the highest SNR. In a volunteer study, 2D-SENSE coronary images were obtained with total reduction factors of 3 and 4. Excellent depiction of the right and left coronary systems was possible in all cases.

Adolescent↗

PubMed2006

Potential and feasibility of parallel MRI at high field.

This survey focuses on the fusion of two major lines of recent progress in MRI methodology: parallel imaging with receiver coil arrays and the transition to high and ultra-high field strength for human applications. As discussed in this paper, combining the two developments has vast potential due to multiple specific synergies. First, parallel acquisition and high field are highly complementary in terms of their individual advantages and downsides. As a consequence, the joint approach generally offers enhanced flexibility in the design of scanning strategies. Second, increasing resonance frequency changes the electrodynamics of the MR signal in such a way that parallel imaging becomes more effective in large objects. The underlying conceptual and theoretical considerations are reviewed in detail. In further sections, technical challenges and practical aspects are discussed. The feasibility of parallel MRI at ultra-high field is illustrated by current results of parallel human MRI at 7 T.

Algorithms↗

PubMed2005

Transmit and receive transmission line arrays for 7 Tesla parallel imaging.

Transceive array coils, capable of RF transmission and independent signal reception, were developed for parallel, 1H imaging applications in the human head at 7 T (300 MHz). The coils combine the advantages of high-frequency properties of transmission lines with classic MR coil design. Because of the short wavelength at the 1H frequency at 300 MHz, these coils were straightforward to build and decouple. The sensitivity profiles of individual coils were highly asymmetric, as expected at this high frequency; however, the summed images from all coils were relatively uniform over the whole brain. Data were obtained with four- and eight-channel transceive arrays built using a loop configuration and compared to arrays built from straight stripline transmission lines. With both the four- and the eight-channel arrays, parallel imaging with sensitivity encoding with high reduction numbers was feasible at 7 T in the human head. A one-dimensional reduction factor of 4 was robustly achieved with an average g value of 1.25 with the eight-channel transmit/receive coils.

Brain↗

PubMed2004

Electrodynamics and ultimate SNR in parallel MR imaging.

The purpose of this article is to elucidate inherent limitations to the performance of parallel MRI. The study focuses on the ultimate signal-to-noise ratio (SNR), which refers to the maximum SNR permitted by the electrodynamics of the signal detection process. Using a spherical model object, it is shown that the behavior of the ultimate SNR imposes distinct limits on the acceleration rate in parallel imaging. For low and moderate acceleration, the ultimate SNR performance is nearly optimal, with geometry factors close to 1. However, for high reduction factors beyond a critical value, the ultimate performance deteriorates rapidly, corresponding to exponential growth of the geometry factor. The transition from optimal to deteriorating performance depends on the electrodynamic characteristics of the detected RF fields. In the near-field regime, i.e., for low B0 and small object size, the critical reduction factor is constant and approximately equal to four for 1D acceleration in the sphere. In the far-field wave regime the critical reduction factor is larger and increases both with B0 and object size. Therefore, it is concluded that parallel techniques hold particular promise for human MR imaging at very high field.

Electromagnetic Fields↗

PubMed2004

Parallel imaging performance as a function of field strength--an experimental investigation using electrodynamic scaling.

In this work, the dependence of parallel MRI performance on main magnetic field strength is experimentally investigated. Using the general framework of electrodynamic scaling, the B0-dependent behavior of the relevant radiofrequency fields at a single physical field strength of 7 T is studied. In the chosen implementation this is accomplished by adjusting the permittivity and conductivity of a homogeneous spherical phantom. With different mixing ratios of decane, ethanol, purified water, N-methylformamide, and sodium chloride, field strengths in the range of 1.5 to 11.5 T are mimicked. Based on sensitivity maps of an eight-coil receiver array, the field-dependent performance of parallel imaging is assessed in terms of the geometry factor g, which reflects noise enhancement in parallel imaging reconstruction. At low field strengths the SNR penalty was nearly independent of B0 and favorably low for 1D reduction factors up to between 3 and 4. At higher field strengths the transition between favorable and prohibitive parallel imaging conditions was found to shift toward higher feasible reduction factors. These findings are in good agreement with previous theoretical predictions. From this agreement it is concluded that parallel MRI at high B0 benefits specifically from onsetting far-field behavior of the involved radiofrequency fields.

Electromagnetic Fields↗