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Biomedical subjects

François Bodic

Publications and source records attributed to François Bodic.

2 recordsLinked to original sources

Bone loss and teeth.

Loss of teeth results in irreversible alveolar bone resorption, and untreated dental disease causes alveolar bone lysis that ultimately leads to loss of teeth. In addition to anchoring the teeth in the alveolar ridge, the maxillary and mandibular bone allows dental restoration procedures, such as construction of root-supported implants, fixed dentures, or removable dentures. However, the functional and cosmetic results depend on the quantity and quality of the maxillary or mandibular bone, which can be affected by many normal and abnormal processes. The alveoli are particularly fragile and labile. Changes in alveolar bone vary considerably across individuals and depend directly on local factors. Many studies have investigated associations between alveolar bone status and bone mass at other skeletal sites. These studies focused chiefly on the course of parodontal disease, alveolar ridge resorption after tooth extraction, and density differences across various mandibular sites. They produced conflicting results, probably because of differences in measurement methods. Measurement sites and methods should be standardized to ensure that reliable and comparable data are obtained. To date, there are few reliable methods for obtaining quantitative measurements of bone mineral content in maxillary and mandibular bone.

Bone Density↗

[Non-invasive evaluation of an injectable bone substitute].

Despite the increasing number of techniques for the preservation of bone ridges after dental avulsion, no precise evaluation of alveolar filling has been performed to date. The criteria of available measurement techniques (probes, retroalveolar or panoramic radiography, and lateral teleradiography) are not sufficiently reliable and precise. This study investigated the reliability of evaluation based on CT images in comparison with retroalveolar radiography (the most precise radiographic technique, providing standardised images), direct measurements, and images obtained in scanning electron microscopy. After a preliminary investigation ex vivo, a study was performed in vivo on three beagles. Mandibular premolars were extracted, and the corresponding alveoli were filled with an injectable bone substitute composed of a calcium phosphate mineral load associated with hydroxypropyl methylcellulose. Measurements performed on CT images relative to visual and automatic detection of density changes and studies of density curves provided better precision than those obtained by retroalveolar radiography.

Animals↗